Whole-lesion Apparent Diffusion Coefficient First- and Second-Order Texture Features for the Characterization of Rectal Cancer Pathological Factors

The objective of this study was to explore the value of whole-volume apparent diffusion coefficient (ADC) features in characterizing pathologic features of rectal cancer. Methods A total of 50 patients who were diagnosed with rectal cancer via biopsy underwent 3-T pretreatment diffusion-weighted imaging. Apparent diffusion coefficient features, including mean, 10th–90th percentile, Entropy and Entropy(H), derived from whole-lesion volumes were compared between pathologic T1–2 and T3 stages, perineural invasion (PNI) present and absent, lymphangiovascular invasion present and absent, and pathological N0 and N+ stage groups. Results Entropy and Entropy(H) were significantly lower in rectal cancers at T1–2 stages than T3. The 90th percentile of rectal cancers with PNI was significantly lower than that of those without PNI. All P
Source: Journal of Computer Assisted Tomography - Category: Radiology Tags: Abdominal Imaging Source Type: research