Cardiovascular risk in Turner syndrome

Publication date: July 2018Source: Revista Portuguesa de Cardiologia (English Edition), Volume 37, Issue 7Author(s): Beatriz Donato, Maria João FerreiraAbstractTurner syndrome is a relatively common genetic disorder of female development, characterized by partial or complete absence of an X chromosome, with a variable clinical presentation. Congenital or acquired cardiovascular disease is highly prevalent and a major cause of early death in this syndrome. The most feared complication is aortic dissection, which can occur at a very young age and requires careful assessment of its risk factors. A systematic literature search identified sixty relevant publications. These were reviewed with regard to the increased risk of cardiovascular disease in women with Turner syndrome, especially in pregnancy. The most common congenital cardiovascular defects are presented and illustrated with appropriate iconography. The current recommendations regarding the screening and monitoring of cardiovascular disease in these patients are discussed.ResumoA síndrome de Turner é uma condição genética relativamente comum, caracterizada pela perda total ou parcial de um cromossoma X, com uma apresentação clínica variável e que afeta o desenvolvimento das mulheres. Nessa síndrome há uma prevalência elevada de doença cardiovascular, congénita e adquirida, que condiciona um risco aumentado de morte prematura. A complicação mais temida é a disseção da aorta, que tende a ocorrer em idade...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research