Autonomic dysfunction in the neurological intensive care unit

AbstractAutonomic dysfunction is common in neuro-critical care patients and may compromise the function of various organs. Among the many diseases causing or being associated with autonomic dysfunction are traumatic brain injury, cerebrovascular diseases, epilepsy, Guillain –Barré syndrome (GBS), alcohol withdrawal syndrome, botulism and tetanus, among many others. Autonomic dysfunction may afflict various organs and may involve hyper- or hypo-activity of the sympathetic or parasympathetic system. In this short overview, we address only a small number of neuro-inten sive care diseases with autonomic dysfunction. In GBS, autonomic dysfunction is frequent and may account for increased mortality rates; rapid changes between sympathetic and parasympathetic hypo- or hyper-activity may cause life-threatening cardiovascular complications. Paroxysmal sympathetic hypera ctivity occurs after brain injury, hypoxia and cerebrovascular and other events, causes paroxysmal tachycardia, hypertension, tachypnoea and hyperthermia and is associated with a poorer prognosis and prolonged intensive care treatment. Other, at times life-threatening autonomic complications with ex aggerated sympathetic activity and compromised baroreflex sensitivity arise during the alcohol withdrawal syndrome triggered by abrupt cessation of alcohol consumption. Botulism and tetanus are examples of life-threatening autonomic dysfunction caused by bacterial neurotoxins. Common neurological di seases, suc...
Source: Clinical Autonomic Research - Category: Research Source Type: research

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CONCLUSIONS: The development of a full triad and additional symptomatology suggests a late recognition of signs and symptoms of WE in schizophrenia. Prophylactic thiamine checks and treatment in patients with schizophrenia are relevant, and if WE is suspected adequate parenteral thiamine supplementation is necessary. Key points Only few cases of schizophrenia-related WE have been published in the literature, though challenges in diagnosing and recognising WE suggest that the vast majority of cases go undetected. Acute thiamine deficiency leads to Wernicke's Encephalopathy. Patients diagnosed with schizophrenia are at risk ...
Source: International Journal of Psychiatry in Clinical Practice - Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research
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Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
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Source: Cardiophile MD - Category: Cardiology Authors: Tags: HBC Austin Flint murmur continuous murmur crescendo-decrescendo murmur delayed diastolic murmur diamond shaped murmur Early diastolic murmur Ejection systolic murmur Gibson’s area Gibson’s murmur Graham steel murmur holosystolic Source Type: blogs
nes R PMID: 32959361 [PubMed - in process]
Source: Revista de Neurologia - Category: Neurology Authors: Tags: Rev Neurol Source Type: research
rrera-Izquierdo M PMID: 32959360 [PubMed - in process]
Source: Revista de Neurologia - Category: Neurology Authors: Tags: Rev Neurol Source Type: research
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Source: Revista de Neurologia - Category: Neurology Authors: Tags: Rev Neurol Source Type: research
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Source: Practical Neurology - Category: Neurology Authors: Tags: Pract Neurol Source Type: research
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Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
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Source: International Angiology - Category: Cardiology Tags: Int Angiol Source Type: research
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Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
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