Multivariate analysis of genome-wide data to identify potential pleiotropic genes for five major psychiatric disorders using MetaCCA

Psychiatric disorders represent a mix of common, chronic, and complex conditions affecting populations with highly prevalence (Gaebel et  al., 2015; Jeste et al., 2015; Merikangas et al., 2010). The main clinical disorders include schizophrenia (SCZ), bipolar disorder (BP), major depression (MD), autism spectrum disorders (ASD) and attention deficit-hyperactivity disorder (ADHD), which are characterized by perceptive and cognitive impairments resulting in abnormalities of behavior, volition, and emotion.

Source: Journal of Affective Disorders - July 17, 2018 Category: Neurology Authors: XiaoCan Jia, YongLi Yang, YuanCheng Chen, ZhiWei Cheng, Yuhui Du, Zhenhua Xia, Weiping Zhang, Chao Xu, Qiang Zhang, Xin Xia, HongWen Deng, XueZhong Shi Source Type: research