Correlation Between Superoxide Dismutase Serum Level Alteration with Neck Metastatic Tumor Post Cisplatin –Paclitaxel Chemotherapy Response in Nasopharyngeal Carcinoma Patients

This study aimed to analyze the correlation between SOD level alteration with neck metastatic tumor response after cisplatin–paclitaxel chemotherapy. This was a cohort study. Thirty samples examined for neck metastasis tumor volume (VTM) and serum SOD were examined with ELISA pre- and postchem otherapy. Statistical significance was defined asp <  0.05. Mean SOD serum level pre-chemotherapy and post-chemotherapy were was 179.5 and 209.1, respectively. Mean tumor metastaic volume pre and post chemotherapy were 127.3 and 62.7, respectively. The correlation test with the result (r) 0.180 andp = 0.340. There was no correlation between SOD serum level alteration with VTM volume post cisplatin–paclitaxel chemotherapy in NPC patients.
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - Category: ENT & OMF Source Type: research