Medical News Today: How do you know if you have pernicious anemia?

Pernicious anemia is a condition where there is a lack of red blood cells. A vitamin B-12 deficiency causes it when the body is unable to absorb this nutrient effectively. Tiredness, shortness of breath, slow reflexes, and pale skin are among the symptoms. Find out here how doctors treat this immune system problem.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Blood / Hematology Source Type: news

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Vitamin B12 (B12), also known as cobalamin, is a water-soluble vitamin. It is a cofactor in DNA synthesis and is involved in the metabolism of every cell of the human body, including the central nervous system. Those with a deficiency of B12 can present with peripheral neuropathy, pernicious anemia, or a cognitive disorder. Previous studies have revealed that a deficiency of B12 is associated with cognitive decline or Alzheimer disease. The data of 2991 people were evaluated from 2 years of the Korean Frailty and Aging Cohort Study, a nationwide multicenter survey. To assess cognitive function, a short form of the Korean ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
We report a 48-year-old gentleman who presented with a 1-week history of dizziness and upper gastrointestinal bleeding. Laboratory evaluation revealed pancytopenia, macrocytosis, toxic neutrophils, hemolysis, suppressed reticulocyte count, positive direct anti-globulin test (DAT), severely reduced B12 levels, and positive anti-intrinsic factor and anti-parietal cell antibodies. He was started on weekly intramuscular B12 supplementation and showed improvement in blood cell counts during follow-up. Recognition of B12 deficiency as a cause of pancytopenia and DAT-positive autoimmune hemolytic anemia can help to avoid unwanted...
Source: Case Reports in Oncology - Category: Cancer & Oncology Source Type: research
VITAMIN B12 deficiency produces a number of eerie effects on the body and the type of symptoms you may experience depend on the underlying cause. One common warning sign associated with B12 deficiency caused by pernicious anaemia is a particular sound.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 12 June 2020Source: International Journal of Surgery Case ReportsAuthor(s): Tommaso Zurleni, Michele Altomare, Giovanni Serio, Filippo Catalano
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
Publication date: Available online 12 June 2020Source: Journal of Dental SciencesAuthor(s): Yu-Hsueh Wu, Ming-Jay Hwang, Yi-Pang Lee, Chun-Pin Chiang
Source: Journal of Dental Sciences - Category: Dentistry Source Type: research
Abstract Objective: Autoimmune conditions tend to cluster in subjects with Addison's disease (AD) and probably also among their relatives. The aim of the study was to estimate the frequency of the endocrine gland-specific autoantibodies in first-degree relatives of patients with AD. Methods: Autoantibodies were investigated in 113 family members using RIA and ELISA assays. The control group comprised 143 age-matched volunteers. Results: Autoimmune diseases were diagnosed in 38.1% relatives. Hashimoto's thyroiditis was found in 20.3%, Graves' disease in 8.0%, vitiligo and type 1 diabetes in 3.5%, whereas ...
Source: European Journal of Endocrinology - Category: Endocrinology Authors: Tags: Eur J Endocrinol Source Type: research
VITAMIN B12 aids the body in essential ways yet some people struggle to absorb the vitamin due to an underlying condition called pernicious anaemia. This can raise one's risk of developing B12 deficiency - here are five early warning signs.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
VITAMIN B12 deficiency is mainly caused by a condition called pernicious anaemia. The autoimmune condition prevents the body from benefiting from the nutrient. And a sign in your vision could indicate you're having trouble absorbing it.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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