Africa:Cracking the Cold Chain Challenge Is Key to Making Vaccines Ubiquitous

[The Conversation Africa] Over the years vaccines have prevented countless cases of disease and saved millions of lives. Infectious diseases like polio, measles, diphtheria, pertussis (whooping cough), rubella (German measles), smallpox, mumps, tetanus and rotavirus used to be common around the world. Today vaccines can prevent them.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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Publication date: Available online 19 January 2019Source: Antiviral ResearchAuthor(s): Anne Leske, Irke Waßmann, Kevin Schnepel, Kyle Shifflett, Julia Holzerland, Linus Bostedt, Patrick Bohn, Thomas C. Mettenleiter, Ana M. Briggiler, Julia Brignone, Delia Enria, Sandra M. Cordo, Thomas Hoenen, Allison GrosethAbstractArenaviruses cause several viral hemorrhagic fevers endemic to Africa and South America. The respective causative agents are classified as biosafety level (BSL) 4 pathogens. Unlike for most other BSL4 agents, for the New World arenavirus Junín virus (JUNV) both a highly effective vaccination (Candi...
Source: Antiviral Therapy - Category: Virology Source Type: research
In conclusion, the findings reported here will help improve animal’s well-being during vaccine trials for CLA and consequently represent significant contribution to animal’s welfare.
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
CONCLUSIONS: NEI promotes the release of a variety of antioxidant factors, enhances the activity of antioxidant enzymes and improves the symptoms of rats with obese asthma. The possible underlying mechanism may be the activation of the Keap1/Nrf2 signaling pathway. PMID: 30657578 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
ConclusionOur study suggests that moxifloxacin is generally tolerated in children and might be considered in disseminated BCGitis cases. Additionally, paying attention to side effects such as liver toxicity is recommended, particularly with the use of other antimycobacterial antibiotics, which could also be hepatotoxic. A moxifloxacin-containing regimen for disseminated BCGitis showed clinical improvement in some patients in this study, although the majority presented the same clinical condition.
Source: International Journal of Pediatrics and Adolescent Medicine - Category: Pediatrics Source Type: research
ConclusionSerological surveillance is important to monitor immune status in population. Susceptibility of young adults to measles, mumps, and rubella indicates need for booster vaccination. With the recent launch of measles-rubella vaccination campaign in India, country specific data will be required to plan periodicity of such campaign, which in turn would be based on accumulation of susceptible individuals in a community. Lastly, inclusion of mumps vaccine in the national universal immunization program needs consideration.
Source: Medical Journal Armed Forces India - Category: General Medicine Source Type: research
Publication date: January 2019Source: Medical Journal Armed Forces India, Volume 75, Issue 1Author(s): J.S.V. Soundarya, Uma Devi Ranganathan, Srikanth P. TripathyAbstractDespite the global efforts made to control tuberculosis (TB) and the large number of available new anti-TB drugs, TB still affects one-third of the world population. The conventional vaccine bacille Calmette–Guérin (BCG) shows varying efficacy in different populations, and there are safety issues in immunocompromised patients. Hence, there is an urgent requirement for a new and better TB vaccine candidate than BCG. There are several alternate...
Source: Medical Journal Armed Forces India - Category: General Medicine Source Type: research
Publication date: Available online 19 January 2019Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): A. Prisilla, P. ChellapandiAbstractC2 toxin produced from Clostridium botulinum serotypes C and D has a potential role in many pathophysiological mechanisms in birds and animals. It has encompassed an ADP ribosyltransferase subunit (C2I) and a translocation/binding subunit (C2II). In the present study, we intended to produce C2I mutant proteins as recombinant subunit vaccines by using glutathione-S-transferase-gene fusion system. The mutants of this study were previously evaluated from their evol...
Source: Comparative Immunology, Microbiology and Infectious Diseases - Category: Infectious Diseases Source Type: research
Publication date: Available online 19 January 2019Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Sona Slosarkova, Jaroslav Bzdil, Katerina Nedbalcova, Jan Matiasovic, Petr Fleischer, Stanislav StanekAbstractMorel's disease is a form of abscessing lymphadenitis of sheep and goats caused by Staphylococcus aureus subspecies anaerobius. In Europe and Africa, the disease is linked to S. aureus of multilocus sequence type 1464. In an outbreak recorded in 2015 in a flock of 530 animals in the district of Nymburk, Czech Republic, Europe, the causative agent was cultured and subsequently confirmed by...
Source: Comparative Immunology, Microbiology and Infectious Diseases - Category: Infectious Diseases Source Type: research
(Natural News) The World Health Organization, a criminal cartel front for the vaccine industry, has just declared war on the so-called “anti-vax” movement. The W.H.O. is the same group that spiked vaccines given to women in Africa with abortion / infertility drugs. The W.H.O. is also the same fraudulent group that falsely declared H5N1 bird...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
CANCER symptoms vary depending on the type you have. Some symptoms, such as a lump or persistent cough, may seem obvious, but with over 200 types of the disease, there are also many more obscure symptoms. Heavy sweating during the night is one.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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