Locally Produced IGF-1 Promotes Hypertrophy of the Ligamentum Flavum via the mTORC1 Signaling Pathway

Conclusions: Enhanced IGF-1 promotes the synthesis of collagen I and collagen III via the mTORC1 signaling pathway, which eventually contributes to hypertrophy of the ligamentum flavum.Cell Physiol Biochem 2018;48:293 –303

https://www.karger.com/Article/FullText/491729

Source: Cellular Physiology and Biochemistry - July 17, 2018 Category: Cytology Source Type: research