Prophylactic intravitreal 5-fluorouracil and heparin to prevent proliferative vitreoretinopathy in high-risk patients with retinal detachment: study protocol for a randomized controlled trial

DiscussionThe present trial uses intraoperative intravitreal 5-FU and LMWH as a prophylactic therapy in high-risk patients with primary RRD, aiming to reduce the incidence of PVR in the group that receives the trial drug. Using laser flare photometry to identify high-risk patients for PVR, this trial will test the effectiveness of a simple treatment to prevent PVR.Trial registrationEudraCT no.: 2015-004731-12, registered October 21, 2015; ClinicalTrials.gov Identifier:NCT02834559, registered July 12, 2016. Protocol version: Version 02. Date: September 18, 2016.
Source: Trials - Category: Research Source Type: clinical trials