Using a single non-inferiority margin or preserved fraction for an entire pharmacological class was found to be inappropriate

To assess the impact on non-inferiority decisions when using a single margin or single preserved fraction (PF) for all non-inferiority trials within a pharmacological class.

Source: Journal of Clinical Epidemiology - July 15, 2018 Category: Epidemiology Authors: Turki A. Althunian, Anthonius de Boer, Rolf H.H. Groenwold, Olaf H. Klungel Tags: Original Article Source Type: research