LAMP1 Overexpression Predicts Poor Prognosis in Diffuse Large B Cell Lymphoma

Lysosomal-associated membrane protein 1 (LAMP1) contributes to tumor metastatic potential and differentiation. We performed immunohistochemical staining to investigate LAMP1 expression levels in 122 diffuse large B cell lymphoma (DLBCL) tumor samples. LAMP1 expression was higher in DLBCL tissues compared with reactive hyperplasia tissues, which was independently associated with worse survivals. LAMP1 expression is associated with poor prognosis in DLBCL.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Tags: Original Study Source Type: research