Dabigatran-induced nephropathy and its successful treatment with Idarucizumab - case report and literature review

Anticoagulant induced renal injury has been previously described with Warfarin treatment.In the last decade direct oral anticoagulants (DOAC) were introduced. They include direct inhibitors of factor Xa (Rivaroxaban, Apixaban, Edoxaban) and a thrombin inhibitor (Dabigatran). There are isolated reports describing acute kidney injury (AKI) due to the use of DOACs.

Source: Thrombosis Research - July 15, 2018 Category: Hematology Authors: Jenan Awesat, Iftach Sagy, Yosef S. Haviv, Anat Rabinovich, Alan Jotkowitz, Elena Shleyfer, Leonid Barski Tags: Review Article Source Type: research