Allograft rejection is associated with the development of functional IgE specific for donor MHC antigens

Donor-specific antibodies (DSA) of the IgG isotype are routinely measured for diagnostic purposes in renal transplant recipients and are associated with antibody-mediated rejection and long-term graft loss.

Source: Journal of Allergy and Clinical Immunology - July 15, 2018 Category: Allergy & Immunology Authors: Andreas M. Farkas, Ulrike Baranyi, Georg A. B öhmig, Lukas Unger, Stefan Hopf, Markus Wahrmann, Heinz Regele, Benedikt Mahr, Christoph Schwarz, Karin Hock, Nina Pilat, Ivan Kristo, Jasmin Mraz, Christian Lupinek, Josef Thalhamer, Gregor Bond, Lorenz Kues Source Type: research