Obesity influences white matter integrity in schizophrenia

Schizophrenia associates with metabolic alterations and increased risk of cardiovascular diseases (CVDs), obesity, metabolic syndrome (MetS), type 2 diabetes, various cancers, and overall mortality (Vancampfort et al., 2013). Possibly due to unhealthy life-style and antipsychotics side-effects (Mitchell et al., 2013), patients with schizophrenia have an increased weight or comorbid obesity in 40-60%. Metabolic alteration are detectable at the earliest stages of illness, and their incidence increases in multi-episode patients (Minichino et al., 2017).
Source: Psychoneuroendocrinology - Category: Psychiatry Authors: Source Type: research