Flexible optically stimulated luminescence band for 1-D < i > in vivo < /i > radiation dosimetry.

Flexible optically stimulated luminescence band for 1-D <i>in vivo</i> radiation dosimetry.
Phys Med Biol. 2018 Jul 12;:
Authors: Kim TJ, Jung K, Fahimian BP, Pratx G
Abstract
In vivo dosimetry helps ensure the accuracy of radiation treatments. However, standard techniques are only capable of point sampling, making it difficult to accurately measure dose variation along curved surfaces in a continuous manner. The purpose of this work is to introduce a flexible dosimeter band and validate its performance using pre-clinical and clinical X-ray sources. Dosimeter bands were fabricated by uniformly mixing BaFBr:Eu storage phosphor powders into a silicone based elastomer. An optical readout device with dual-wavelength excitation was designed and built to correct for non-uniform phosphor density and extract accurate dose information. Results demonstrated significant correction of the non-uniform readout signal and excellent dose linearity up to 8 Gy irradiation using a pre-clinical 320 kV X-ray system. Beam profile measurements were demonstrated over a long distance of ~30 cm by placing multiple dosimeters in a single line and stitching the results. The performance of the dosimeters was also tested using a clinical linear accelerator (6 MV) and compared to radiochromic film. Once bias corrected, the bands displayed a linear dose response over the 1.02 - 9.36 Gy range (R2 &gt; 0.99). The proposed system can be further improve...

Source: Physics in Medicine and Biology - July 12, 2018 Category: Physics Authors: Kim TJ, Jung K, Fahimian BP, Pratx G Tags: Phys Med Biol Source Type: research