Reduced anterior cingulate grey matter volume in painful hand osteoarthritis

ConclusionOur study found evidence of reduced ACC grey matter volume in participants with hand arthritis that persisted after treatment with centrally acting analgesics pregabalin and duloxetine, respectively. The sustained changes observed in the ACC in our study could reflect the relatively short duration of treatment, or that the differences observed are irreversible volume changes due to chronic pain that are established over time.
Source: Rheumatology International - Category: Rheumatology Source Type: research