Smokers up to 45% more likely to suffer from irregular heart beats

Researchers from  Imperial College London found that for every 10 cigarettes smoked a day, the risk of suffering from atrial fibrillation, which is a cause of stroke, increases by 14 per cent.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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AbstractBackgroundDigitalis glycosides are employed for rate control of atrial fibrillation. Recent studies suggested potential harmful effects of digitalis monotherapy and combination with antiarrhythmic drugs. The aim of the present study was to assess the prevalence and potential impact of digitalis therapy on outcome in patients undergoing catheter ablation of supraventricular arrhythmias.Methods and resultsThe German Ablation Registry is a nationwide, prospective registry with a 1-year follow-up investigating 12,566 patients receiving catheter ablations of supraventricular arrhythmias in 52 German centres. The present...
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research
Publication date: Available online 21 February 2019Source: Canadian Journal of CardiologyAuthor(s): Marco Proietti, Deirdre A. Lane, Giuseppe Boriani, Gregory Y.H. LipAbstractIn recent years the management of AF patients has progressively and substantially changed due to the introduction of new treatments and the availability of new data regarding the epidemiology and clinical management of these patients. In the last two years alone, there have been seven new guidelines or guideline updates that have been published, introducing new recommendations and significantly revising previously published ones. Two updates for Canad...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
This study comprised 2,516 hypertensive patients who had had at least two serum creatinine measurements over a four-year period. An eGFR reduction of ≥10% per year has been deemed as high-eGFR and a reduction in eGFR of less than 10% per year as a low decline. The end-points were: coronary artery disease, stroke, transitory ischemic accident, peripheral arterial disease, heart failure, atrial fibrillation, death from any cause. Cox regression analyses adjusted for potentially confounding factors were conducted. RESULTS: 2,354 patients with low rate of eGFR decline and 149 with high-rate of eGFR decline were analyze...
Source: American Journal of Hypertension - Category: Cardiology Authors: Tags: Am J Hypertens Source Type: research
ABSTRACT Objectives: To compare warfarin and dabigatran for thromboembolic event prevention in patients with nonvalvular atrial fibrillation or atrial flutter. Methods: This was a retrospective cohort of participants with nonvalvular atrial fibrillation or atrial flutter using either warfarin or dabigatran in a reference center in Brazil. Results: There were 112 patients (mean age 65.5 years), with 55.3% using warfarin. The median duration of follow-up was 1.9 years for warfarin and 1.6 years for dabigatran (p = 0.167). Warfarin patients had a higher median of medical appointments per year (8.3 [6.8-10.4] vs 3.1 [2.3-4.2], p
Source: Arquivos de Neuro-Psiquiatria - Category: Neurology Source Type: research
Publication date: Available online 20 February 2019Source: American Heart JournalAuthor(s): Eric D. Peterson, Veronica Ashton, Yen-Wen Chen, Bingcao Wu, Alex C. SpyropoulosBackgroundThere are limited data regarding clinical outcomes and healthcare resource utilization of direct oral anticoagulants (DOACs) in patients with atrial fibrillation (AF) who are morbidly obese (body mass index>40 kg/m2 or body weight> 120 kg).MethodsUsing data from 2 US healthcare claims databases, we identified patients initiating rivaroxaban or warfarin who had ≥1 medical claim with an AF diagnosis, a diagnostic code for ...
Source: American Heart Journal - Category: Cardiology Source Type: research
Conclusion:  Incorrect computerized interpretation of atrial fibrillation, combined with the failure of the ordering physician to correct the erroneous interpretation, can result in the initiation of unnecessary, potentially harmful medical treatment as well as inappropriate use of medical resources. Greater efforts should be directed toward educating physicians about the electrocardiographic appearance of atrial dysrhythmias and in the recognition of confounding artifacts.
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
AbstractWarfarin is dependent on multiple hepatic enzymes for metabolism while apixaban is a substrate for P-glycoprotein (P-gp) transport and hepatic CYP3A4 metabolism. The aim of this analysis was to assess the impact of interacting medication use on the treatment effects of apixaban versus warfarin. Outcomes were compared between apixaban and warfarin using Cox proportional hazards modeling according to the use of interacting medications at randomization in ARISTOTLE (n  = 18,201). Interacting medications for apixaban were identified as combined P-gp and 3A4 inhibitors or inducers while interacting medicat...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
Condition:   Atrial Fibrillation Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Apixaban (Eliquis);   Drug: Warfarin Sponsors:   Bayer;   Janssen, LP Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Abbott has developed an implantable device that continuously monitors the heart rhythm and allows for communication with a clinician via a smartphone. The paperclip-sized device, called the Confirm Rx insertable cardiac monitor (ICM), requires no re-...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiology Exclusive Source Type: blogs
ConclusionThe present study revealed a significant number of ECG findings during continued ECG monitoring for AF in patients with cryptogenic stroke. Apart from AF (17.5% during the first 1.5  years), other clinical relevant arrhythmias requiring, e.g., pacemaker implantations, were observed. With respect to these findings, we recommend to extend ILR monitoring to the end of battery life. However, acceptance of continued ECG monitoring until battery depletion was poor; in 71 patients (6 4%), the ILR were explanted before the end of battery life.Trial registrationRegistered at ClinicalTrials.gov: NCT02641678.
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research
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