Low levels of psychological distress can increase risk of arthritis
Southampton General Hospital researchers assessed 16,485 British adults over a three-year period to make the conclusion, published in the Journal of Psychosomatic Research.
ConclusionSeveral radiographic variables of destructive and growth abnormalities in children with hip JIA have reasonable reproducibility. We suggest that future studies on clinical validity focus on assessing only reproducible radiographic variables.
Publication date: Available online 13 July 2018Source: International OrthodonticsAuthor(s): Joël Ferri, Julien Potier, Jean-Michel Maes, Hervey Rakotomalala, Ludovic Lauwers, Mickael Cotelle, Romain NicotSummaryRheumatic diseases (RD) of the temporomandibular joints (TMJs) are increasingly frequent affections and unfortunately often confused with “classic” manducatory dysfunctions (disk dislocation, myofascial pain syndroms). Their diagnosis is mandatory, given the major subsequent craniofacial disorders, which may occur (mandibular condylar hypoplasia, facial hyperdivergence, remodelling of the condylar u...
CONCLUSIONS: In high BMI RA patients both SJC and DAS28 seem to be undervalued by clinical assessment when compared to US. PMID: 29998844 [PubMed - as supplied by publisher]
CONCLUSIONS: The US scan of 3 target joints showed a high sensitivity in detecting subclinical active synovitis in RA patients in clinical remission and can be feasible in the routine assessment of these patients. PMID: 29998842 [PubMed - as supplied by publisher]
CONCLUSIONS: Our study identifies that both IAS and PTI cause MCPj swelling, where PTI is almost as frequent as IAS as a cause of swelling. The reliability of PTI is at least as good as for IAS. PMID: 29998840 [PubMed - as supplied by publisher]
CONCLUSIONS: Our results demonstrate that two thirds of patients with PsA in Iceland who are treated with TNFi would not have qualified for the randomised clinical trials performed leading up to the registration of the medications. Further studies with regards to whether outcomes are different between those who met the inclusion criteria and those who did not remain to be performed. PMID: 29998835 [PubMed - as supplied by publisher]
CONCLUSIONS: Over a 10-year follow-up period, reclassification revealed significant heterogeneity in the diagnosis of seronegative RA. Therefore, seronegative arthritis should not be studied as a homogenous entity. PMID: 29998832 [PubMed - as supplied by publisher]
CONCLUSIONS: Overall, these results suggest that IL-17, TRAIL and TNF-α sustain bone tissue inflammation associated with decrease of calcified component. To do so, they act redundantly each other, to amplify the inflammatory response in the bone. In conclusion, unravelling novel molecular targets within the bone-cytokine network represents a platform for innovative treatment of bone diseases due to immunological diseases such as psoriatic arthritis. PMID: 29998830 [PubMed - as supplied by publisher]
Authors: Watanabe T, Hattori T, Ogawa Y, Jodo S PMID: 29998828 [PubMed - as supplied by publisher]
CONCLUSIONS: IB was well-tolerated and comparable to IO, with no additional safety signals identified. The results suggest superior survival of IB over IO over the first 2 years. PMID: 29998827 [PubMed - as supplied by publisher]