Three-Dimensional Spheroid Culture Increases Exosome Secretion from Mesenchymal Stem Cells

Conclusion:These results suggested that 3D spheroid culture produces more exosomes than 2D culture and the non-adherent round cell morphology itself might be a causative factor. The result of the present study could provide useful information to develop an optimal process for the mass production of exosomes.
Source: Tissue Engineering and Regenerative Medicine - Category: Biotechnology Source Type: research