A Useful marker in the assessment of remission and activation of disease in patients with rheumatoid arthritis: Serum human neutrophil peptides 1-3.

CONCLUSION: In the present study, patients with an active disease had significantly higher serum HNP 1-3 levels compared to patients in remission. In this respect, serum HNP 1-3 can be a useful marker in the assessment of disease activity and remission in patients with RA. PMID: 29991120 [PubMed - as supplied by publisher]
Source: Journal of Back and Musculoskeletal Rehabilitation - Category: Orthopaedics Tags: J Back Musculoskelet Rehabil Source Type: research

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We present the results of a long term observational study of RA-1 (Ayurvedic drug) used in the treatment of rheumatoid arthritis (RA).ObjectiveThe objective was to study safety of long term use of RA-1 for treatment of rheumatoid arthritis (RA).Materials and methodsOn completion of a 16 week randomized controlled study, 165 consenting volunteer patients were enrolled into a three year open label phase (OLP) study. Patients were symptomatic with persistent active disease and naïve for disease modifying anti-rheumatic drugs (DMARD). 57 patients were on fixed low dose prednisone. Patients were examined every 10–14 ...
Source: Journal of Ayurveda and Integrative Medicine - Category: Complementary Medicine Source Type: research
ConclusionsUsing an evidence-based approach followed by expert consensus, this initiative should improve the assessment and optimization of adherence in chronic inflammatory rheumatic disorders.
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Publication date: Available online 19 September 2018Source: Joint Bone SpineAuthor(s): Minh Vu Chuong Nguyen, Annie Adrait, Athan Baillet, Candice Trocmé, Jacques-Eric Gottenberg, Philippe Gaudin
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Publication date: Available online 19 September 2018Source: Joint Bone SpineAuthor(s): Renaud Felten, Florence Scher, Jean Sibilia, François Chasset, Laurent ArnaudABSTRACTThere have been many advances in the diagnosis and therapeutic management of Systemic Lupus Erythematosus (SLE) over the past decades. Following more than eleven centuries of therapeutic uncertainty, the discovery of the therapeutic properties of glucocorticoids is without any doubt one of the most significant advance in the field of autoimmune diseases. The many progresses made by rapidly growing chemical industry of the 19th century chemistry ha...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Optetrak Logic CC Stem Extension, 22mm x 160mm The OPTETRAK Logic CC Total Knee System is indicated for use in skeletally mature individuals undergoing primary surgery for total knee replacement due to osteoarthritis, osteonecrosis, rheumatoid arthritis and/or post-traumatic degenerative problems.
Source: Medical Device Recalls - Category: Medical Devices Source Type: alerts
ConclusionsTocilizumab appears to be effective and safe in RA in clinical practice. The optimised regimen appears to be effective in most patients in remission, even when they change from IV to SC.ResumenObjetivoEvaluar la efectividad y la seguridad de tocilizumab (TCZ) en pacientes con artritis reumatoide (AR) en práctica clínica; la optimización de dosis y el cambio de formulación intravenosa (iv) a subcutánea (sc).Material y métodosEstudio observacional retrospectivo. Se incluyó a 53 pacientes con AR tratados con TCZ. El desenlace principal fue efectividad de TCZ en la se...
Source: Reumatologia Clinica - Category: Rheumatology Source Type: research
Publication date: Available online 20 September 2018Source: Best Practice &Research Clinical RheumatologyAuthor(s): Jonathan Chan, Dafna GladmanAbstractSpondyloarthritis (SpA) represents a group of common diseases that share a number of characteristic clinical manifestations including peripheral arthritis, spondylitis, enthesitis, and dactylitis. Additionally, they can often be associated with extra-articular manifestations including psoriasis, anterior uveitis, and inflammatory bowel disease. The two most widely studied clinical phenotypes are ankylosing spondylitis and psoriatic arthritis.Although a number of biologi...
Source: Best Practice and Research Clinical Rheumatology - Category: Rheumatology Source Type: research
Adalimumab, a fully human antibody to tumor necrosis factor (TNF), was first approved by the Food and Drug Administration (FDA) in 2002 for the treatment of rheumatoid arthritis. In 2008, it was approved for treatment of polyarthritis juvenile idiopathic arthritis and has since been approved for other pediatric indications that cross several subspecialties, including dermatology, gastroenterology and ophthalmology. Thus, it is important for a growing number of pediatricians, including those in primary care, to be aware of the safety profile of this widely used biologic medication.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: The Editors' Perspectives Source Type: research
ConclusionGene expression of IL6 was down-regulated in RA patients, especially CRP-negative patients. Moreover, four SNPs of such cytokine may have a role in RA risk.
Source: Alexandria Journal of Medicine - Category: General Medicine Source Type: research
(Natural News) According to a study, “ibuprofen is associated with increased blood pressure and hypertension” compared to celecoxib given to patients who had osteoarthritis or rheumatoid arthritis and increased risk of cardiovascular disease. The results from the PRECISION-ABPM (Prospective Randomized Evaluation of Celecoxib Integrated Safety versus Ibuprofen or Naproxen Ambulatory Blood Pressure Measurement) study revealed...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
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