Subglottic Hemangioma: understanding the association with facial segmental hemangioma in a beard distribution
A subglottic hemangioma (SGH) is a benign tumor of infancy that can cause severe obstruction of the airway. Infantile hemangiomas, in general, are the most common head and neck tumor in children, affecting 4 –5% of the pediatric population. This retrospective cohort study characterizes subglottic infantile hemangiomas at a single vascular anomaly center over a 5-year period (2013 – 2017) during the era of propranolol treatment.
radRounds Radiology Network and Idonia are partnering to provide a professional Image Exchange Platform to facilitate collaboration, exchange and research on COVID-19 cases.Users can upload, store, organize, review, and share DICOM Images.Idonia is a secure (HIPAA compliant) online platform for medical image exchange and delivery. The platform can serve as a repository for relevant clinical cases, which radiologists can access and visualize thanks to the DICOM viewer of the platform. This allows radiologists to create their own network to collaborate and share relevant cases with other radiologists.Idonia and radRounds hav...
Conclusion: The response to propranolol treatment in IH patients was associated with the gene polymorphism of CYP2D6 (rs1135840). A low-dose propranolol regimen was effective and safe in young infants with IH. The change of serum VEGF levels after one month's treatment could not be used to predict the response rate to propranolol. PMID: 32219146 [PubMed - as supplied by publisher]
Epigenomics, Ahead of Print.
Purpose: To evaluate the subfoveal choroidal thickness (SFCT) and vascular architecture in the fellow eyes of patients with circumscribed choroidal hemangioma (CCH). Methods: In this retrospective observational study, patients were selected from outpatient ophthalmology clinics at the Memorial Sloan Kettering Cancer Center and Vitreous Retina Macula Consultants of New York. Subfoveal choroidal thickness was measured using enhanced depth imaging spectral domain optical coherence tomography from the outer portion of Bruch membrane to the choroidal–scleral interface. Choroidal vascular architecture was qualitativel...
Abstract Infantile hemangiomas (IHs) are common benign vascular tumours in infants (estimated prevalence 5% to 10%).1 Oral propranolol is currently the first-line treatment for complicated proliferative IHs.2 It is approved by the US Food and Drug Administration and the European Medicines Agency for treating complicated IHs, but questions remain regarding the optimal modalities of use.3 We conducted an international survey to assess practices in prescribing oral propranolol for IHs among practitioners dealing with IHs worldwide. PMID: 32221977 [PubMed - as supplied by publisher]
PMID: 32213223 [PubMed - as supplied by publisher]
No abstract available
In conclusion, we identified CHOP and HO-1 inhibition, and BMP9 as potential therapeutic options for PVOD. PMID: 32209028 [PubMed - as supplied by publisher]
Publication date: June 2020Source: Human Pathology: Case Reports, Volume 20Author(s): Akira Tsuneto, Hiroaki Kawano, Naoe Kinoshita, Kiyoyuki Eishi, Koji Maemura
Abstract: In the past decades, there was a considerable advance in regard to recognition of morphologic findings and classification of several benign and malignant vascular proliferations. In 2002, attention was called by Requena et al to a new variant of cutaneous hemangioma named acquired elastotic hemangioma. In this article, a case of acquired elastotic hemangioma is reported with documentation of clinical, dermatoscopic, histopathological, and immunohistochemical findings. A systematic review of the previously 49 reported cases is provided. The criteria for clinical and histopathological diagnosis are highlighted.