HUWE1 upregulation has tumor suppressive effect in human prostate cancer cell lines through c-Myc

ConclusionHUWE1 overexpression could functionally suppress CaP development bothin vitro and in vivo, possibly by inverse regulation on c-Myc.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research

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Fifty years ago, in a golden moment of television comedy shows, Rowan &Martin’s Laugh-In program regularly featured “The Flying Fickle Finger of Fate” award.  Wikipedia says it “recognized actual dubious achievements by public individuals or institutions.” Do a Google search.  You’ll quickly see how popular this award became. Yes, I’m dating myself by going back 50 years.  But mine is the generation that often becomes obsessed with being given “the finger” by doctors for digital rectal exams (DRE) looking for prostate cancer. And it is in that context...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Mainstream media Oncology/Hematology Source Type: blogs
(MedPage Today) -- Stereotactic body radiation therapy demonstrates efficacy in longer follow-up study
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(CNN) — You can protect yourself from cancer by eating organic, a new study suggests. Those who frequently eat organic foods lowered their overall risk of developing cancer, a study published Monday in JAMA Internal Medicine finds. Specifically, those who primarily eat organic foods were more likely to ward off non-Hodgkin lymphoma and postmenopausal breast cancer compared to those who rarely or never ate organic foods. Led by Julia Baudry, an epidemiologist at Institut National de la Sante et de la Recherche Medicale in France, a team of researchers looked at the diets of 68,946 French adults. More than three-quarte...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Cancer Local TV Organic Source Type: news
Professor Siobhan McClelland is fleeing Wales, claiming flaws in the Welsh NHS is affecting everything from diagnosis rates to patient care. Her husband is battling prostate cancer.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Osteoporosis is a common complication of androgen deprivation therapy (ADT). In this large Swedish cohort study consisting of a total of nearly 180,000 older men, we found that those with prostate cancer and ADT have a significantly increased risk of futur...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Men with advanced prostate cancer lived 11 percent longer when treated with radiation therapy and standard treatment in a trial in Britain.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
For men with newly diagnosed metastatic prostate cancer who have low metastatic burden, radiotherapy to the prostate provides significant survival benefits, say the STAMPEDE investigators.Medscape Medical News
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Publication date: Available online 21 October 2018Source: The LancetAuthor(s): Christopher C Parker, Nicholas D James, Christopher D Brawley, Noel W Clarke, Alex P Hoyle, Adnan Ali, Alastair W S Ritchie, Gerhardt Attard, Simon Chowdhury, William Cross, David P Dearnaley, Silke Gillessen, Clare Gilson, Robert J Jones, Ruth E Langley, Zafar I Malik, Malcolm D Mason, David Matheson, Robin Millman, J Martin RussellSummaryBackgroundBased on previous findings, we hypothesised that radiotherapy to the prostate would improve overall survival in men with metastatic prostate cancer, and that the benefit would be greatest in patients...
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: Available online 21 October 2018Source: The LancetAuthor(s): Luca Boeri, Vidit Sharma, R Jeffrey Karnes
Source: The Lancet - Category: General Medicine Source Type: research
Research, published inThe Lancet, suggests that radiation therapy combined with standard hormonal therapy can extend the survival in patients with locally spread prostate cancer. News Medical
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
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