Automated psychological therapy using immersive virtual reality for treatment of fear of heights: a single-blind, parallel-group, randomised controlled trial

Publication date: Available online 11 July 2018Source: The Lancet PsychiatryAuthor(s): Daniel Freeman, Polly Haselton, Jason Freeman, Bernhard Spanlang, Sameer Kishore, Emily Albery, Megan Denne, Poppy Brown, Mel Slater, Alecia NicklessSummaryBackgroundEngaging, interactive, and automated virtual reality (VR) treatments might help solve the unmet needs of individuals with mental health disorders. We tested the efficacy of an automated cognitive intervention for fear of heights guided by an avatar virtual coach (animated using motion and voice capture of an actor) in VR and delivered with the latest consumer equipment.MethodsWe did a randomised trial of automated VR versus usual care. We recruited adults aged older than 18 years with a fear of heights by radio advertisements in Oxfordshire, UK. We diagnosed fear of heights if participants scored more than 29 on the Heights Interpretation Questionnaire (HIQ). We randomly allocated participants by computer in a 1:1 ratio to either automated VR delivered in roughly six 30-min sessions administered about two to three times a week over a 2-week period (intervention group) or to usual care (control group). Randomisation was stratified by severity of fear of heights. The research team, who were unaware of the random allocation, administered three fear-of-height assessments, at baseline (0 weeks), at the end of treatment (2 weeks), and at follow-up (4 weeks). The primary outcome measure was HIQ score (range 16–80, with higher sc...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research

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ConclusionsLVRS is an effective operation with overall improvement in functional status and quality of life among appropriately selected patients.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Publication date: Available online 17 November 2018Source: The Annals of Thoracic SurgeryAuthor(s): Kimberly E. McHugh, William T. Mahle, Matthew A. Hall, Mark A. Scheurer, Michael-Alice Moga, John Triedman, Susan C. Nicolson, Venugopal Amula, David S. Cooper, Marcus Schamberger, Michael Wolf, Lara Shekerdemian, Kristin M. Burns, Kathleen E. Ash, Dustin M. Hipp, Sara K. Pasquali, Pediatric Heart Network InvestigatorsAbstractBackgroundThe Pediatric Heart Network Collaborative Learning Study (PHN CLS) increased early extubation rates after infant Tetralogy of Fallot (TOF) and coarctation (CoA) repair across participating sit...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsTreatment with warfarin or aspirin both lead to similar outcomes after surgical bAVR. Combining aspirin with warfarin may lead to a small decrease in thromboembolism and mortality but is accompanied by increased bleeding. For TAVR patients, aspirin is equivalent to DAPT for reducing thromboembolism and mortality, with a possible decrease in bleeding.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Publication date: Available online 17 November 2018Source: The Annals of Thoracic SurgeryAuthor(s): Hideki Tsubota, Genichi Sakaguchi, Yoshio Arai, Jun Iida, Akira Marui
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsIn patients with significant bleeding following cardiac surgery, PCC administration seems to be more effective than FFP in reducing perioperative blood transfusions. No additional risks of thromboembolic events or other adverse reactions were observed. Randomized controlled trials are needed to definitively establish the safety of PCC in cardiac surgery.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Publication date: Available online 17 November 2018Source: The Annals of Thoracic SurgeryAuthor(s): Michael C. Sinclair
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Publication date: Available online 17 November 2018Source: The Annals of Thoracic SurgeryAuthor(s): Masaya Tamura, Isao Matsumoto, Yusuke Tanaka, Daisuke Saito, Shuhei Yoshida, Seiichi Kakegawa, Tomoyasu Kumano, Yosuke Shimizu, Hiroyasu Tamamura, Tsuyoshi Takanaka, Hirofumi TakemuraAbstractBackgroundThe aim of this study was to compare outcomes of primary treatment with stereotactic body radiation therapy (SBRT) versus sublobar resection (SLR) for clinical stage I non-small cell lung cancer (NSCLC) in patients with medical comorbidities.MethodsConsecutive patients who underwent SBRT (n=106) or SLR (wedge resection: n=100 a...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
CONCLUSIONS: These results highlight a key role of the nucleus accumbens in cigarette craving in schizophrenia and suggest that the subjective valuation of cigarette cues is increased in this population. Similar neurofunctional studies on cravings for other psychoactive substances in schizophrenia are warranted. PMID: 30445892 [PubMed - as supplied by publisher]
Source: Journal of Dual Diagnosis - Category: Addiction Tags: J Dual Diagn Source Type: research
CONCLUSIONS: Polysubstance use, conceptualized within the multimorbidity perspective, is associated with increased severity of PTSD symptoms among veterans with dual diagnoses requiring complex interventions, the evaluation of which will require innovative trial designs. PMID: 30444189 [PubMed - as supplied by publisher]
Source: Journal of Dual Diagnosis - Category: Addiction Tags: J Dual Diagn Source Type: research
Publication date: Available online 17 November 2018Source: Meat ScienceAuthor(s): Xiao Lu, Yimin Zhang, Lixian Zhu, Xin Luo, David L. HopkinsAbstractThe effect of superchilled storage (SC, −4 °C) on shelf life and quality characteristics of M. longissimus lumborum from Chinese Yellow cattle compared with traditional chilling (TC, 2 °C) and frozen storage (−18 °C) was studied. The shelf life of beef steaks held at −4 °C extended to 12 weeks based on the total volatile basic nitrogen (TVB-N) value, which was 2.4 times longer than steaks stored at 2 °C. As the storage time inc...
Source: Meat Science - Category: Food Science Source Type: research
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