Gold(I)-Catalyzed Tandem Cycloisomerization of 1,5-Enyne Ethers via Hydride Transfer.

Gold(I)-Catalyzed Tandem Cycloisomerization of 1,5-Enyne Ethers via Hydride Transfer.
Angew Chem Int Ed Engl. 2018 Jul 10;:
Authors: Wong HNC, Lu XL, Lyu MY, Peng XS
Abstract
A novel gold-catalyzed tandem protocol, initiated by hydride transfer in the presence of catalytic (C6F5)3PAuCl/AgSbF6, towards the formation of fused polycyclic ring systems has been achieved. This tandem reaction provides a rapid access to various fused polycyclic species in a single chemical operation, leading to stereospecific formation of two carbon-carbon bonds and three rings.
PMID: 29989283 [PubMed - as supplied by publisher]

Source: Angewandte Chemie - July 10, 2018 Category: Chemistry Authors: Wong HNC, Lu XL, Lyu MY, Peng XS Tags: Angew Chem Int Ed Engl Source Type: research