The Real-World Cost-Effectiveness of Coronary Artery Bypass Surgery Versus Stenting in High-Risk Patients: Propensity Score-Matched Analysis of a Single-Centre Experience
ConclusionsAt early follow-up, high-risk subgroups had lower ICERs than the overall cohort when CABG was compared with PCI. A personalised, multidisciplinary approach to treatment of patients may enhance cost containment, as well as improving clinical outcomes following revascularisation strategies.
Publication date: 1 August 2018Source: Nitric Oxide, Volume 78Author(s): Xiaohong Liu, Xin Xu, Ruru Shang, Yingjie ChenAbstractPatients with chronic kidney disease have an increased cardiovascular morbidity and mortality. It has been recognized that the traditional cardiovascular risk factors could only partially explain the increased cardiovascular morbidity and mortality in patients with chronic kidney disease. Asymmetric dimethylarginine (ADMA) and N-monomethy l-arginine (L-NMMA) are endogenous inhibitors of nitric oxide synthases that attenuate nitric oxide production and enhance reactive oxidative specie generation. I...
Conclusions: The incidence of death without stroke was 9-fold higher than that of stroke, leading to biased estimates of stroke risk with traditional time-to-event methods. Statistical methods that appropriately account for competing risks should be used to mitigate this bias.
Publication date: June 2018Source: International Journal of Gerontology, Volume 12, Issue 2Author(s): Feng-Ching Liao, Chia-Ying Hsiao, Chuan-Lei Chao, Chun-Han Cheng, Meng-Ruey Wu, Min-I. Su, Chun-Yen Chen, Kung-Te WangSummaryBackgroundThe influence of renal impairment on long-term mortality in Taiwanese patients with an ICD was uncertain. The aim of our study was to examine the impact of moderate to severe CKD on outcome in patients with ICD implantation for secondary prevention in Taiwan.MethodsFrom 2005 to 2013, patients who underwent ICD implantation who were survivors of sudden cardiac arrest or unstable hemodynamics...
Publication date: Available online 27 June 2018Source: Revista Española de Cardiología (English Edition)Author(s): Maria Mahmood, Gregory Y.H. LipAbstractBoth atrial fibrillation (AF) and chronic kidney disease (CKD) are highly prevalent, especially with increasing age and associated comorbidities, such as hypertension, diabetes, heart failure, and vascular disease. The relationship between both AF and CKD seems to be bidirectional: CKD predisposes to AF while onset of AF seems to lead to progression of CKD. Stroke prevention is the cornerstone of AF management, and AF patients with CKD are at higher risk of ...
We present a case of CHT-induced CDE in a 64-year-old male with multiple cardiac risk factors.
Publication date: April 2018Source: Archives of Cardiovascular Diseases Supplements, Volume 10, Issue 2Author(s): S. Antit, B. Ben Kaab, I. Slama, S. Chenik, C. Gharbi, I. Boussabeh, L. Zakhama, S. BenyoussefBackgroundAlthough the improvement of the diagnostic and therapeutic means, the impact of chronic kidney disease (CKD) on mortality and morbidity in patients acute coronary syndrome (ACS) is still underestimated. The aim of our study is to determine the epidemiological, clinical and follow-up particularities of ACS in patients with CKD.MethodsWe conducted a retrospective descriptive study on 100 patients hospitalized i...
ConclusionIn a large US-based outpatient registry, we found that a quarter of adults with T2D had a diagnosis of HF, which was predominantly HFpEF. Although certain T2D medication use in patients with HF appeared consistent with evidence (less use of thiazolidinediones), others appeared contrary to evidence (less use of metformin and SGLT2 inhibitors).
ConclusionsHarmony Outcomes will assess the CV safety of albiglutide in patients with T2DM and CV disease. Trials of other agents in the glucagon-like peptide-1 receptor agonist class have shown CV benefit for only some of these medications, possibly due to differences in trial design or instead due to differences in drug structure or metabolism. Harmony Outcomes will provide information critical to our understanding of this heterogenous class of glucose-lowering agents.
The patient had numerous bouts of ascites, but this time, the fluid's color and composition heralded a new and ominous diagnosis. A 75-year-old woman with cirrhosis secondary to nonalcoholic steatohepatitis was admitted with abdominal pain. Her medical history also included coronary artery bypass grafting, congestive heart failure with a reduced ejection fraction of 40%, chronic kidney disease, stage III, type 2 diabetes, and obesity.
Conclusions SCH is associated with an increased CVD risk and all-cause mortality, particularly in participants with high CVD risk. PMID: 29978767 [PubMed - as supplied by publisher]
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