Medical News Today: What is pregabalin?

Pregabalin oral capsule is used to treat neuropathic pain and fibromyalgia. It ’s also used with other seizure drugs to treat partial onset seizures. Pregabalin oral capsule is only available as the brand-name drug Lyrica. It's not available as a generic drug. Learn about side effects, warnings, dosage, and more.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Pharmacy / Pharmacist Source Type: news

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CONCLUSIONS: The FIQR and FAS cut-off points for remission, mild, moderate and high disease severity are valid measures which can be easily applied in daily clinical practice. PMID: 30325304 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
In the seven years since the original Wheat Belly book hit bookstores and turned the nutritional world topsy-turvy and millions of people have engaged in a grain-free lifestyle, many unique lessons have been learned. Even though I had engaged the practices of this lifestyle for a number of years and in thousands of people before I broadcast these ideas through books, expanding the audience to many more people yielded feedback on an enormous scale, new lessons that even surprised me. Among the new lessons learned along the way: Plantar fasciitis—I did not expect to have so many people report that this painful conditi...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates bowel flora gluten gluten-free grain-free grains Inflammation Weight Loss Source Type: blogs
This study suggests mindfulness (which was not linked with greater activity) may also be useful in decreasing depression, but by other means, possibly through creating distance from unhelpful thoughts that may arise around pain or the experience of disability.  As cross-sectional research, we can’t draw clear causal conclusions from the new findings, but they do help us refine our understanding of which mechanisms are more likely to increase pain acceptance. The findings may also help pain management professionals focus their methods, providing people with the ground from which they can build and sustain a life ...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Health Source Type: blogs
This study suggests mindfulness (which was not linked with greater activity) may also be useful in decreasing depression, but by other means, possibly through creating distance from unhelpful thoughts that may arise around pain or the experience of disability.  As cross-sectional research, we can’t draw clear causal conclusions from the new findings, but they do help us refine our understanding of which mechanisms are more likely to increase pain acceptance. The findings may also help pain management professionals focus their methods, providing people with the ground from which they can build and sustain a life ...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Health Source Type: blogs
Assessment of hand function and disability in fibromyalgia. Z Rheumatol. 2018 Oct 15;: Authors: Devrimsel G, Turkyilmaz AK, Beyazal MS, Karkucak M Abstract OBJECTIVE: Fibromyalgia, a potentially debilitating chronic pain syndrome, is a chronic disease. We aimed to compare the hand function of fibromyalgia (FM) patients and healthy individuals and to demonstrate the relationship between hand disability and FM. PATIENTS AND METHODS: The study was consisted of 40 female patients with FM and 30 healthy controls. All participants were evaluated for pain threshold measurements,...
Source: Zeitschrift fur Rheumatologie - Category: Rheumatology Authors: Tags: Z Rheumatol Source Type: research
ConclusionsStatic evoked pain measures suggested BP-related pain inhibitory dysfunction in FM. In contrast, for pain sensitization as indexed by SREP, FM displayed the expected BP-related inhibitory effects. BP-related pain modulation is manifested in FM differentially for static versus dynamic pain indicators. Use of both types of evoked pain measures may be valuable in the study of mechanisms underlying altered pain modulatory systems in FM.
Source: International Journal of Psychophysiology - Category: Psychiatry & Psychology Source Type: research
Fibromyalgia syndrome (FMS) is a clinical condition characterized by chronic widespread pain, fatigue, and non-refreshing sleep, and is frequently associated with cognitive impairment 13. FMS prevalence in the general adult population ranges between 2% and 6% 13. Exercise and cognitive behavioral therapy (CBT) are strongly recommended, in addition to pharmacologic therapy, as essential parts of its treatment 3,13. However, one of the challenges in assessing the effectiveness of CBT is that it involves various interventions 53.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
Conclusion: Studies that use a comprehensive model of personality present a different theoretical approach and use alternatively the Big-Five model, Eysenck's and Cloninger's models. The use of a comprehensive model of personality and the control of psychopathological disorders, such as anxiety and depression, seem to be very relevant for a better understanding of a specific personality profile associated with fibromyalgia. PMID: 30294356 [PubMed]
Source: Clinical Practice and Epidemiology in Mental Health - Category: Psychiatry Tags: Clin Pract Epidemiol Ment Health Source Type: research
CONCLUSIONS: No significant relationship was found between FM patients' subjective appraisal of cognitive deficit and objective cognitive scores on all computerised subtests. However, subjective appraisal of cognitive impairment was found to be strongly and significantly related to patients' functional ability. Therefore, we suggest reconsidering the definition of this index score (SSS-Cog) and propose developing novel and more accurately defined tools in order to measure cognitive impairment in FM patients, for both diagnostic and epidemiological purposes. PMID: 30299249 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Authors: Pamfil C, Choy EHS Abstract Pain is the most common symptom in rheumatic diseases. However, the severity of pain does not correlate with pathology. The lack of an objective test for pain results in clinicians consider pain in patients with fibromyalgia as psychological. Research over the last two decade using functional neuroimaging especially functional MRI scan have demonstrated objectively that patients with fibromyalgia were not malingering. Pain processing is complex and multiple regions of the brain are involved. One consistent finding is decrease activity in regions of the brain involved in pain inh...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
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