Medical News Today: What is pregabalin?

Pregabalin oral capsule is used to treat neuropathic pain and fibromyalgia. It ’s also used with other seizure drugs to treat partial onset seizures. Pregabalin oral capsule is only available as the brand-name drug Lyrica. It's not available as a generic drug. Learn about side effects, warnings, dosage, and more.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Pharmacy / Pharmacist Source Type: news

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FIBROMYALGIA symptoms usually consist of widespread pain in the body, but other signs are also linked to the condition, such as feeling tired. If you have the symptoms for at least three months you should go see your GP for help.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Bidari A, Ghavidel Parsa B, Ghalehbaghi B Abstract Fibromyalgia (FM) is a contested illness with ill-defined boundaries. There is no clearly defined cut-point that separates FM from non-FM. Diagnosis of FM has been faced with several challenges that occur, including patients' health care-seeking behavior, symptoms recognition, and FM labeling by physicians. This review focuses on important but less visible factors that have a profound influence on under- or over-diagnosis of FM. FM shows different phenotypes and disease expression in patients and even in one patient over time. Psychosocial and cultural fac...
Source: Korean Journal of Pain - Category: Anesthesiology Tags: Korean J Pain Source Type: research
Abstract In this article, we present the development of a methodological diagnostic tool for the field of public health from an interdisciplinary perspective that articulates the biological, psychological, and social dimensions of human health from a post-structuralist and feminist perspective and epistemology. In prior research, we have developed a methodology for the study of chronic pain without an organic cause, or fibromyalgia (FM), that we call the psychosocial diagnosis of gender. That work addresses the analysis of the research object itself and, above all, a critical reconceptualization of health in general. We ha...
Source: Saude e Sociedade - Category: International Medicine & Public Health Source Type: research
CONCLUSION: PFM and SFM are equivalent regarding symptom burden. PSD scores are more informative about severity and severity within diagnosis than dichotomization into FM/non-FM. Studies of FM versus "healthy individuals," or FM versus other diseases, are inherently defective, while studies of FM and PSD in RA offer the opportunity to have meaningful comparison groups, because there are no readily available unbiased appropriate controls for PFM. PMID: 30008459 [PubMed - as supplied by publisher]
Source: J Rheumatol - Category: Rheumatology Authors: Tags: J Rheumatol Source Type: research
ConclusionThe daily intake of melatonin improved the sleep quality, increased the aMT6-s levels and the total antioxidant capacity in patients with fibromyalgia.
Source: Journal of Applied Biomedicine - Category: Biotechnology Source Type: research
This study involved eighty RA patients divided equally according to rheumatoid factor (RF) positivity. Modified Health Assessment Questionnaire, disease activity score in 28-joints (DAS 28), visual analogue scale of pain, Short Form Health Survey for mental and physical health, fibromyalgia questionnaire, RA Articular Damage score and radiological joint damage by van der Heijde modification were assessed. Serum level for serotonin was measured for all patients.ResultsThe mean age of seronegative patients was 41.7 ± 10.7 years; 36 females and 4 males and of seropositive (44.9 ± 12.9&nb...
Source: The Egyptian Rheumatologist - Category: Rheumatology Source Type: research
In this study, the effect of the consumption of Annona muricata L. (Annonaceae) leaves (AM) was investigated on a model for intermittent cold stress (ICS)-induced fibromyalgia in mice. An aqueous extract of AM was investigated in experiments involving 60 five-week-old female mice C57BL/6J.The animals were allocated into six groups (n = 10). Groups (I) Healthy control, (II) ICS control, and (III) ICS + acetaminophen (0.5%), were all fed a standard diet, while groups (IV) and (V) received standard diets supplemented with 15% (AM15) and 30% (AM30) aqueous extract of AM leaves, respectively. Group (VI) received a stand...
Source: PharmaNutrition - Category: Nutrition Source Type: research
Publication date: Available online 20 June 2018Source: Brain, Behavior, and ImmunityAuthor(s): Xin Zhang, Jane E. Hartung, Andrey V. Bortsov, Seungtae Kim, Sandra C. O'Buckley, Julia Kozlowski, Andrea G. NackleyAbstractFunctional pain syndromes, such as fibromyalgia and temporomandibular disorder, are associated with enhanced catecholamine tone and decreased levels of catechol-O-methyltransferase (COMT; an enzyme that metabolizes catecholamines). Consistent with clinical syndromes, our lab has shown that sustained 14-day delivery of the COMT inhibitor OR486 in rodents results in pain at multiple body sites and pain-related...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
ConclusionHerbal medicine utilisation among patients admitted to integrative inpatient care is common. While predictors of herbal medicine use appear to be in line with previous findings, there is a need for more in-depth examination of patients’ motivations for the use of herbal medicine to further the understanding of their health behaviours and needs.
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research
ConclusionThese results suggest that the preadministration of YKS attenuated the development of antinociceptive morphine tolerance and that the inhibition of orexin A secretion may be one mechanism underlying this phenomenon.
Source: Integrative Medicine Research - Category: Complementary Medicine Source Type: research
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