Medical News Today: What is lisinopril?

Lisinopril is an oral medication used to treat hypertension (high blood pressure) and heart failure. Learn about side effects, warnings, dosage, and more.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Pharmacy / Pharmacist Source Type: news

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Publication date: Available online 21 March 2019Source: MitochondrionAuthor(s): Hamza El Hadi, Roberto Vettor, Marco RossatoAbstractCardiovascular disease is the leading cause of diabetes-related morbidity and mortality. It is widely accepted that heart failure risk is increased in diabetic patients even after adjusting for coronary artery disease and hypertension. Mitochondria are the center of fatty acid (FA) and glucose metabolism and thus are likely to be impacted by impaired metabolism associated with diabetes. Although the cause of this increased heart failure risk is multifactorial, increasing evidence points toward...
Source: Mitochondrion - Category: Biochemistry Source Type: research
ConclusionPreoperative ECG Strain was associated with higher risk of ME onset after TAVR for severe AS.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Publication date: April 2019Source: Archives of Cardiovascular Diseases Supplements, Volume 11, Issue 2Author(s): A. Carboni, C. Bielmann, S. Rignault-Clerc, N. Rosenblatt-VelinLCZ696 treatment reduces the mortality and the risk of hospitalization of patients with hypertension or heart failure with a preserved ejection fraction by 20%. The LCZ696 molecule associates both an angiotensin receptor blocker (valsartan) and an inhibitor of neprilysin (NEP, sacubitril). NEP is an endopeptidase able to degrade several factors such as the natriuretic peptides, angiotensin II, bradykinin, endothelin-1.Despite the cardioprotective ef...
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Publication date: April 2019Source: Archives of Cardiovascular Diseases Supplements, Volume 11, Issue 2Author(s): A. Méloux, L. Rochette, M. Maza, F. Bichat, J.C. Beer, F. Chagué, Y. Cottin, M. Zeller, C. Vergely-VandriesseBackgroundGrowth differentiation factor 15 (GDF15) is an emerging biomarker in cardiovascular (CV) diseases. GDF15 is weakly expressed in normal condition but increased in pathological situations such as inflammation, oxidative stress, and left ventricular remodeling. Recent data suggest GDF15 as a marker in heart failure (HF).PurposeWe aimed to identify the determinants of GDF15 circulatin...
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
ConclusionsIn summary, the SHR PMI model has a good predictive value and can be used as preclinical model for the evaluation of new therapeutic strategy in HFrEF [1], [2].
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Conclusionsin line with human disease, our results show that hypertensive rats are more prone to develop signs of HF after MI than normotensive rats. SHR PMI should be considered as a relevant preclinical model for the efficacy assessment of new HFrEF therapeutic strategies.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
The objective of the study is to explore differences of beta-blocker regimens (vasodilating vs. non-vasodilating beta-blockers) for substrate oxidation during in high-intensity intermittent exercise (HIIE) in chronic heart failure and reduced ejection fraction (HFrEF). Eighteen CHF males (58.8 ± 9 years), 8 under use of β 1 specific beta-blockers+alfa 1-blocker and 10 using β 1 non-specific beta-blockers, were randomly assigned to 4 different HIIE, in a cross-over design. The 4 protocols were: 30 seconds (A and B) or 90 seconds (C and D) at 100% peak power output, with passive (A and C) or active recovery ...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
Population studies from the United States have established that African ancestry is accompanied by a higher cardiovascular risk, translating in a higher incidence of heart failure (HF) and greater 5-year mortality [1]. This may be, in part, due to more prevalent clinical risk factors for HF/death among Blacks, such as higher rates of hypertension, diabetes mellitus, and obesity and also more frequent genetic predisposition toward earlier and more severe cardiovascular disease.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research
Raised blood pressure with age, hypertension, is a major downstream consequence of low-level biochemical damage and cellular dysfunction, converting it into high-level structural damage in the body and brain. Hypertension is an important proximate contributing cause of ultimately fatal age-related conditions of the cardiovascular system, kidneys, brain, and lungs, among others. Pressure damage in delicate tissues degrades function in many organs, particularly in the central nervous system where there is little to no regeneration capable of reversing that damage. More subtly, hypertension also causes heart muscles to enlarg...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Authors: Zhang S, Zhang W, Zhou G Abstract Stroke causes disability and high mortality, while it can be prevented by increasing public awareness of risk factors. The common known risk factors are hypertension, atrial fibrillation, heart failure, smoking, alcohol consumption, low physical activity, overweight and hypercholesterolemia. However, the deep understanding of risk factors is limited. Moreover, more risk factor emerges in recent years. To further increase the awareness of risk factors for stroke prevention, this review indicates the reasonable application of antihypertensive agents according to the age-depe...
Source: Journal of the National Medical Association - Category: General Medicine Tags: J Natl Med Assoc Source Type: research
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