Medical News Today: What is lisinopril?

Lisinopril is an oral medication used to treat hypertension (high blood pressure) and heart failure. Learn about side effects, warnings, dosage, and more.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Pharmacy / Pharmacist Source Type: news

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The FDA announced last week a voluntary recall of several high blood pressure and heart failure medications containing valsartan due to a cancerous impurity. Some valsartan drugs were found to contain N-nitrosodimethylamine (NDMA), a compound that is classified as a probable human carcinogen. Get the full story at our sister site, Drug Delivery Business News. The post FDA recalls heart failure, blood pressure drugs due to cancerous contaminant appeared first on MassDevice.
Source: Mass Device - Category: Medical Devices Authors: Tags: Cardiovascular Food & Drug Administration (FDA) Pharmaceuticals Recalls Regulatory/Compliance Wall Street Beat Teva Pharmaceuticals Source Type: news
Ajmer Singh, Yatin MehtaJournal of Anaesthesiology Clinical Pharmacology 2018 34(2):161-165 Heart failure (HF) is a complex clinical syndrome that results from any structural or functional impairment of ventricular filling or ejection of blood. American College of Cardiology Foundation / American Heart Association 2013 guidelines have classified HF into two categories: (i) HF with reduced (≤40%) ejection fraction (HFrEF) or systolic HF, and (ii) HF with preserved (≥50%) ejection fraction (HFpEF) or diastolic HF. Risk factors for HFpEF include age more than 70 years, female gender, hypertension, wide pu...
Source: Journal of Anaesthesiology Clinical Pharmacology - Category: Anesthesiology Authors: Source Type: research
This study examined the association between alcohol consumption and risk for HF in older adults with hypertension. The study analysed data from a cohort of 6083 participants aged 65-84 years at baseline (1995 –2001) followed for a median of 10.8 years during and after the Second Australian National Blood Pressure Study. Frequency and amount of alcohol consumption were self-reported at baseline and during the clinical trial.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research
Every day we care for older hospitalized adults who are at risk for orthostatic hypotension. Take the case of Mr. Smith. Mr. Smith, is a 83 year-old gentleman who had been admitted to the hospital with congestive heart failure; additionally, he had multiple comorbid diagnoses including diabetes mellitus, hypothyroidism, depression, hyperlipidemia, and hypertension. His medications included furesomide 40  mg twice a day, potassium 20 meq daily, lisinopril 40 mg daily, levothyroxine 100 mcg daily and sertraline 100 mg daily.
Source: Geriatric Nursing - Category: Nursing Authors: Source Type: research
Conclusions: This study pointed out that in the serum studies focused on cardiovascular disease, let-7i and miR-16 had the best performance, while SNOU6 and 5S were not suitable as reference gene. This study indicate that the selection of an optimal reference genes is important to get an accurate result in serum miRNA studies, the findings are of clinical significance to guide the further miRNA studies or tests. PMID: 29997921 [PubMed]
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
FDA is alerting the public about a voluntary recall of several drug products containing valsartan, used to treat high blood pressure and heart failure
Source: Food and Drug Administration - Category: American Health Source Type: news
July 13, 2018 -- The U.S. Food and Drug Administration is alerting health care professionals and patients of a voluntary recall of several drug products containing the active ingredient valsartan, used to treat high blood pressure and heart failure....
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Conclusions: Understanding the burden of disease for common chronic conditions and for combinations of these conditions is useful for delivering high-quality primary care that could be tailored for individuals with combinations of chronic conditions.
Source: Medical Care - Category: Health Management Tags: Brief Reports Source Type: research
Publication date: October 2018Source: Clinica Chimica Acta, Volume 485Author(s): Rong Yu, Xuebin Han, Xun Zhang, Yun Wang, Tong WangAbstractCorin is a type II transmembrane serine protease that is highly expressed in the heart and plays a physiological role in the activation of natriuretic peptides. Corin is expressed primarily in myocytes, and it can enter the circulation. Circulating soluble corin has been found to be associated with various cardiovascular diseases, such as hypertension, heart failure, myocardial infarction, preeclampsia, and stroke. All these findings indicate that circulating soluble corin has the pote...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Publication date: September 2018Source: Clinica Chimica Acta, Volume 484Author(s): Gjin NdrepepaAbstractUric acid (UA) is an end product of purine metabolism in humans and great apes. UA acts as an antioxidant and it accounts for 50% of the total antioxidant capacity of biological fluids in humans. When present in cytoplasm of the cells or in acidic/hydrophobic milieu in atherosclerotic plaques, UA converts into a pro-oxidant agent and promotes oxidative stress and through this mechanism participates in the pathophysiology of human disease including cardiovascular disease (CVD). Most epidemiological studies but not all of ...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
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