Effect of Adherence to Antihypertensive Medication on the Long-Term Outcome After Hemorrhagic Stroke in KoreaNovelty and Significance Hemorrhagic Stroke

Hypertension is the single most important risk factor for hemorrhagic stroke, a leading cause of mortality and disability worldwide. Adherence to antihypertensive medication is essential to achieving strict blood pressure control, but poor adherence is common in clinical practice. We evaluated adherence to antihypertensive medication in patients with acute hemorrhagic stroke and its effects on long-term outcome. This was a retrospective cohort study based on a nationwide health insurance claims database in South Korea. We included 1872 hypertensive patients who were admitted with acute hemorrhagic stroke during 2002 to 2013 (1354 cases of intracerebral hemorrhage and 518 cases of subarachnoid hemorrhage). Adherence to antihypertensive medication was calculated using the proportion of days covered by any antihypertensive medication throughout the follow-up period (categorized into poor 80%) and treated as a time-dependent variable. Primary outcome was defined as a composite of recurrent stroke (hemorrhagic or ischemic), myocardial infarction, or all-cause mortality. Time-dependent Cox proportional hazard regression analyses were performed. During the mean follow-up period of 4.45 years, 634 patients had the primary outcome. The proportion of patients with good adherence to antihypertensive medication was 46.8% at 1 year, 43.2% at 3 years, and 41.7% at 5 years of follow-up. Compared with good adherence, the adjusted hazard ratio (95% confidence interval) for the primary outcome...
Source: Hypertension - Category: Cardiology Authors: Tags: Secondary Prevention, Hypertension, Compliance/Adherence, Intracranial Hemorrhage Original Articles Source Type: research

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Publication date: March 2020Source: Research in Developmental Disabilities, Volume 98Author(s): Yael Barak-Levy, Na'ama Atzaba-PoriaAbstractIn accordance with the determinant of parenting model (Belsky, 1984), a conceptual model is proposed in which parental stress mediates the links between child, proximal, and distal risk factors and parental behavior. Participants were 156 families with children aged 4–7 years (M = 5.64 years, SD = 0.62; 59 % boys); research group: 75 two-parent families having children with mild intellectual disability (MID); control group: 81 two-parent families with typically developed ...
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
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Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
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Source: Neuroscience Research - Category: Neuroscience Source Type: research
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Source: Neurochemistry International - Category: Neuroscience Source Type: research
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Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
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Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
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Source: Psychiatr News - Category: Psychiatry Tags: ajp in advance cannabis cannabis use disorder Deborah Hasin National Epidemiologic Survey on Alcohol and Related Conditions pain Source Type: research
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Source: Gaceta Sanitaria - Category: International Medicine & Public Health Tags: Gac Sanit Source Type: research
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Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
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Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
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