Long term survival of a dog with disseminated Aspergillus deflectus infection without definitive treatment

Publication date: Available online 10 July 2018Source: Medical Mycology Case ReportsAuthor(s): Peter F. Bennett, Jessica J. Talbot, Patricia Martin, Sarah E Kidd, Mariano Makara, Vanessa R. BarrsAbstractCanine disseminated fungal infection by Aspergillus species carries a guarded to grave prognosis as they often rapidly progress and are refractory to treatment with many euthanased soon after diagnosis. This case report describes a 2.5 year old female spayed German Shepherd Dog diagnosed with disseminated Aspergillus deflectus infection for which definitive treatment was declined by the owners. With only palliative management the dog survived three years and two months before succumbing to chronic kidney disease.
Source: Medical Mycology Case Reports - Category: Biology Source Type: research

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Publication date: Available online 17 July 2018Source: Pharmacological ResearchAuthor(s): Omar Emiliano Aparicio-Trejo, Edilia Tapia, Laura Gabriela Sánchez-Lozada, José Pedraza-ChaverriAbstractNowadays, chronic kidney disease (CKD) is considered a worldwide public health problem. CKD is a term used to describe a set of pathologies that structurally and functionally affect the kidney, it is mostly characterized by the progressive loss of kidney function. Current therapeutic approaches are insufficient to avoid the development of this disease, which highlights the necessity of developing new strategies to reve...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
ConclusionIn patients admitted for AHF without renal failure or CKD, WRF with HC is associated with a better prognosis, similar to that of patients without WRF, and should therefore be reclassified as ‘pseudo-WRF’.ResumoIntroduçãoAlterações na função renal com aumento da creatinina têm sido associadas a maior mortalidade em doentes com insuficiência cardíaca aguda (ICA). Já a hemoconcentração na ICA tem-se associado a redução da mortalidade, é também uma causa de elevação da creatinina. Av...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
This study investigated the association between systemic inflammation and chronic kidney disease (CKD), and whether this association changes with aging in adults, by using neutrophil-to-lymphocyte ratio (NLR) as an inflammation marker.Materials and methodsA total of 2954 adults (1815 men and 1139 women) who attended a health examination at a medical center in central Taiwan were included for the final cross-sectional analysis.ResultsCompared with participants aged
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Publication date: Available online 3 November 2017Source: Clinica Chimica ActaAuthor(s): Sahapab Anuwatmatee, Shudi Tang, Ben J. Wu, Kerry-Anne Rye, Kwok Leung OngAbstractThe association between fibroblast growth factor 21 (FGF21) and kidney function has been extensively studied in recent years in both animal and human studies. However, the exact functional role of FGF21 in the kidney remains unclear. Previous animal studies have shown that administration of FGF21 ameliorates kidney function, morphological glomerular abnormalities, dyslipidemia, hyperglycemia, insulin resistance, oxidative stress and obesity. In human stud...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Authors: Patel J, Bridgeman MB Abstract Etelcalcetide (Parsabiv) for hyperparathyroidism in adults with chronic kidney disease on hemodialysis. PMID: 30013296 [PubMed]
Source: P and T - Category: Drugs & Pharmacology Tags: P T Source Type: research
This study suggested that A. valentinus oil is a potential candidate to be used as a safe biocontrol agent to prevent food crops from fungal diseases and improve product quality and safety.
Source: Food Bioscience - Category: Food Science Source Type: research
Conclusions: Thiol/disulphide homeostasis was not affected in tinea versicolor. According to our findings, oxidative stress seems to have no role in the pathogenesis of tinea versicolor. PMID: 30008649 [PubMed]
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
Publication date: October 2018Source: Biocatalysis and Agricultural Biotechnology, Volume 16Author(s): Marília Crivelari da Cunha, Laura Carvalho Silva, Hélia Harumi Sato, Ruann Janser Soares de CastroAbstractMicrobial L-asparaginase have been used as a therapeutic agent in the treatment of acute lymphoblastic leukemia and Hodgkin's disease. In addition to clinical use, L-asparaginases have been used in foods to reduce the formation of acrylamide. L- asparaginase production is carried out mainly by submerged fermentation (SmF). However, solid-state fermentation (SSF) offers potential benefits compared with su...
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
Publication date: August 2018Source: Journal of Bioscience and Bioengineering, Volume 126, Issue 2Author(s): Mayumi Maeda, Masashi Tokashiki, Midori Tokashiki, Keiko Uechi, Susumu Ito, Toki TairaAwamori is a traditional distilled liquor in the Ryukyu Islands, made from steamed rice by the action of the black-koji mold Aspergillus luchuensis and awamori yeast Saccharomyces cerevisiae. One of the specific flavors in aged awamori kusu is vanillin, which is derived from ferulic acid (FA) in rice grains. FA is released from the cell wall material in the rice grain by ferulic acid esterase produced by A. luchuensis. Through...
Source: Journal of Bioscience and Bioengineering - Category: Biomedical Science Source Type: research
Conclusions: The results of our study point towards a link between CXCL12 and LVH as well as blood pressure control among patients with CKD, supporting the thesis that CXCL12 may be regarded as a new potential uremic toxin.Cardiorenal Med 2018;8:249 –258
Source: Cardiorenal Medicine - Category: Urology & Nephrology Source Type: research
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