Pulmonary Hypertension, Mortality, and Cardiovascular Disease in CKD and ESRD Patients: A Systematic Review and Meta-analysis
ConclusionsPulmonary hypertension is associated with a substantially increased risk for death and cardiovascular events in patients with CKD and ESRD. Risk is higher in patients with ESRD receiving dialysis compared with patients with CKD stages 1 to 5. Understanding the effect of interventions to lower pulmonary artery pressure on the survival of these patents awaits their evaluation in randomized controlled trials.
Conclusions: The developed web DB system contributed to improve the health condition of the health program participants by providing necessary information to the health professionals at the right time. This case report could be a reference for other researcher to develop web databases for their own context, especially in developing countries. PMID: 30788180 [PubMed]
Pediatric hypertension (HTN) is commonly due to secondary causes such as renal parenchymal disease or renal artery stenosis (RAS). But, the impact of accessory renal arteries on the renin-angiotensin-aldosterone feedback system and potential for causing HTN is not known. First proposed by Glodny et al in 2001, parenchyma supplied by ‘accessory’ vessels may have lower blood pressure (BP) than the dominant renal parenchyma triggering renin secretion. The purpose of this study is to evaluate the safety and efficacy of accessory renal artery embolization (ARAE) in children presenting with suspected renal artery HTN.
Catheter malfunction and occlusion remains a common detriment of dialysis catheters. Analysis of RA anatomy on 3D imaging reviewed that the anterior posterior diameter of the RA is longer than the lateral. Preclinical studies with a dialysis catheter designed to be compatible with this feature of RA anatomy are presented herein.
Central vein stenosis often precludes creation of permanent AV access for hemodialysis. The HeRO graft is indicated for use in patients with central venous pathology. However, some patients have undergone prior insertion of multiple central venous stents that “jail” supraclavicular access and are often considered inappropriate candidates for the HeRO graft. The purpose of this study was to assess the feasibility of HeRO graft insertion through stent interstices.
ABSTRACTIn the general population and in heart disease, pulmonary hypertension (PH) is a strong and independent risk factor for mortality and adverse cardiovascular outcomes. We performed a systematic review and meta ‐analysis of longitudinal cohort studies of individuals with chronic kidney disease (CKD) of any‐stage (also including end‐stage kidney disease –ESKD‐ and kidney transplantation) stratified according to presence/absence of PH.18 eligible studies (10740 participants) were retrieved. PH had an overall pooled prevalence (PP) of 33% (95% CI 28 ‐42) and portended a higher risk of all‐cause mortali...
INTRODUCTION: Atypical hemolytic uremic syndrome (aHUS) is a complement mediated thrombotic microangiopathy that predominantly affects the kidneys although extra-renal manifestations are common. In the pre-eculizumab era, 40-65% of patients either died or had end stage renal disease (ESRD) at 1 year. Long-term renal and cardiovascular outcomes are less well described in the eculizumab era. We conducted this cohort study to describe the renal and cardiovascular outcomes of adult survivors of aHUS, both on and off continued eculizumab therapy.METHODS: Patients with aHUS were identified from the prospective Complement Associa...