Probability of Opioid Prescription Refilling After Surgery: Does Initial Prescription Dose Matter?

Conclusions: The probability of refilling prescription opioids after surgery was not correlated with initial prescription strength, suggesting surgeons could prescribe smaller prescriptions without influencing refill requests. Future research that examines the interplay between pain, substance abuse, and mental health could inform strategies to tailor opioid prescribing for patients.
Source: Annals of Surgery - Category: Surgery Tags: Original Articles Source Type: research

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Publication date: Available online 20 July 2018Source: The LancetAuthor(s): Fatima Marinho, Valéria Maria de Azeredo Passos, Deborah Carvalho Malta, Elizabeth Barboza França, Daisy M X Abreu, Valdelaine E M Araújo, Maria Teresa Bustamante-Teixeira, Paulo A M Camargos, Carolina Cândida da Cunha, Bruce Bartholow Duncan, Mariana Santos Felisbino-Mendes, Maximiliano Ribeiro Guerra, Mark D C Guimaraes, Paulo A Lotufo, Wagner Marcenes, Patricia Pereira Vasconcelos Oliveira, Marcel de Moares Pedroso, Antonio L Ribeiro, Maria Inês Schmidt, Renato Azeredo TeixeiraSummaryBackgroundPolitical, economic...
Source: The Lancet - Category: General Medicine Source Type: research
ConclusionThis endoscopy-based study revealed the most common histology of benign SB tumors were hamartoma and adenoma, and malignant ones were lymphomas, GISTs, adenocarcinomas and metastatic cancers. Most of them were male gender, except for GISTs, and with proximal location, except for lymphomas. Further large-scale investigation efforts are warranted to elucidate the epidemiology of SB tumors.
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
Publication date: 1 November 2018Source: Materials Science and Engineering: C, Volume 92Author(s): Amir reza Ariamoghaddam, Bahman Ebrahimi-Hosseinzadeh, Ashrafalsadat Hatamian-Zarmi, Razi SahraeianAbstractObesity as a dominant problem in developed countries which is known to be basic step of so many diseases is subjected to find a solution for in this work. Curcumin containing polyvinyl alcohol-gelatin nanofibers which ranging from 200 to 250 nm in diameter as a transdermal drug delivery system for declining volume of subcutaneous adipose tissue is investigated here. Morphology and synthesis method of nanofibers is desi...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: 1 November 2018Source: Materials Science and Engineering: C, Volume 92Author(s): Chander Amgoth, D S Doddapaneni Suman Joshi, Gangappa Dharmapuri, Mohan LakavathuAbstractSynthesis and characterization of the di-block copolymer (di-BCP) of [(BenzA)-b-(PCL)] between benzyl alcohol (BenzA) and poly-ɛ-caprolactone (PCL) follow the development of micelles has been carried out. These developed [(BenzA)-b-(PCL)] based micelles are acting as an adjunct to assemble and arrange gold nanoparticles (AuNPs) in particular shape. Polymeric micelle driving randomly arranged AuNPs to form hollow core-shell (hCS) type mor...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
In this study, silica aerogels were prepared using water-glass precursor based on two drying strategies, namely conventional freeze drying (C-FD) and spray freeze drying (S-FD). It was known that the pore structure of silica aerogel can be optimized uniformly based on S-FD method when tert-butyl alcohol is directly utilized as a solvent. As a result, silica aerogels obtained by the S-FD method are monolithic with high thermal stability and low thermal conductivity, showing a great potential of thermal insulation materials for high-temperature environment.
Source: Materials Letters - Category: Materials Science Source Type: research
Publication date: 15 October 2018Source: Materials Letters, Volume 229Author(s): Konstantin A. Milakin, Udit Acharya, Jiří Hodan, Miroslava Trchová, Jaroslav Stejskal, Patrycja BoberAbstractPoly(aniline-co-1,3-phenylenediamine) cryogels were prepared by a simple one-step approach involving oxidative cryopolymerization of respective comonomers in the presence of poly(vinyl alcohol) stabilizer. Resulting cryogels were characterized by SEM, Raman spectroscopy, conductivity and tensile measurements. The addition of small amounts (1 mol%) of 1,3-phenylenediamine into copolymerization with aniline allows for the...
Source: Materials Letters - Category: Materials Science Source Type: research
In this report, a so-called proton permselective composite membrane was prepared specifically for waste acid reclamation by electrodialysis. Above all, a porous supporting membrane was prepared from polysulfone via classical wet phase inversion technology. Therein appropriate amount of sulfonated polysulfone (SPSF) was added to adjust its microstructure. Subsequently, a hydrophilic composite layer, such as Poly(ethylene imine) layer or Poly(vinyl alcohol) layer, was used to endow the proton permeability based on the unique transport mechanism of protons in which water molecules play an important role. ATR-FTIR and SEM were...
Source: Journal of Membrane Science - Category: Materials Science Source Type: research
A literature analysis shows ketamine is as effective as morphine for short-term pain relief in emergency departments but had more nonsevere side effects.Medscape Medical News
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Emergency Medicine News Source Type: news
Publication date: Available online 20 July 2018Source: NeuroscienceAuthor(s): Shivakumar Subbanna, Vikram Joshi, Balapal S. BasavarajappaAbstractPostnatal ethanol exposure has been shown to cause persistent defects in hippocampal synaptic plasticity and disrupt learning and memory processes. However, the mechanisms responsible for these abnormalities are less well studied. We evaluated the influence of postnatal ethanol exposure on several signaling and epigenetic changes and on expression of the activity-regulated cytoskeletal (Arc) protein in the hippocampus of adult offspring under baseline conditions and after a Y-maze...
Source: Neuroscience - Category: Neuroscience Source Type: research
This article reviews this relationship and provides recommendations for management. Keywords: Insomnia, sleep disorder, psychiatric disorder, depression, psychosis, schizophrenia, anxiety disorder Insomnia affects 25 million people in the United States annually and leads to an estimated $100 billion health care burden. Insomnia has also been shown to be a causal factor in other medical and psychiatric disorders, cognitive impairments, accidents, absenteeism, and reduced quality of life.1 The cost of not treating insomnia is more than the cost of treating insomnia.2 Insomnia as a symptom is seen in up to one third of the Un...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Review anxiety disorder depression insomnia psychiatric disorder psychosis schizophrenia sleep disorder Source Type: research
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