Pharmacokinetics of Doripenem in Healthy Koreans and Monte Carlo Simulations to Explore Optimal Dosage Regimens in Patients With Normal and Enhanced Renal Function

Conclusions:
These results suggest that dosage adjustment such as increasing the dose or lengthening the infusion time should be considered in patients with normal or enhanced renal function.

Source: Therapeutic Drug Monitoring - July 11, 2018 Category: Drugs & Pharmacology Tags: Original Article Source Type: research