Medical News Today: What is dexamethasone?
Dexamethasone oral tablet is a prescription medication used to treat conditions such as inflammation, allergic reactions, ulcerative colitis, and adrenal insufficiency. It's available as a generic drug and as the brand-name drugs DexPak and Decadron. Learn about side effects, warnings, dosage, and more.
AbstractReal-world data on regimens for relapsed/refractory multiple myeloma (RRMM) represent an important component of therapeutic decision-making. This multi-centric, retrospective, observational study conducted by the treating physicians evaluated the effectiveness and safety of ixazomib-lenalidomide-dexamethasone (IRd) in 155 patients who received ixazomib via early access programs in Greece, the UK, and the Czech Republic. Median age was 68 years; 17% had an Eastern Cooperative Oncology Group performance status ≥ 2; median number of prior therapies was 1 (range 1–7); 91%, 47%, and 17% had receive...
This study reflects the novel IBD treatment targets via the immune system ’s pathway, reporting the latest treatments that regulate the M1/M2 macrophages distribution in a way to favor IBD.
Authors: Grassi G, Morelli V, Ceriotti F, Polledri E, Fustinoni S, D'Agostino S, Mantovani G, Chiodini I, Arosio M Abstract PURPOSE: The current cut-offs for the diagnosis of adrenal insufficiency (AI) have been established using outdated immunoassays. We compared the cortisol concentrations measured with Roche Cortisol I (R1), the newly available Roche Cortisol II (R2), and liquid chromatography tandem mass spectrometry (LC-MS/MS), the gold standard procedure to measure steroids in patients undergoing the corticotropin (ACTH) test. METHODS: We enrolled 30 patients (age 47 ± 21 years) ...
Condition: Inflammatory Bowel Disease Patients Intervention: Sponsor: Assiut University Not yet recruiting
Conditions: Coronavirus Infection; Pneumonia, Viral; Acute Respiratory Distress Syndrome Intervention: Drug: Dexamethasone Sponsors: Luiz F. L. Reis, Ph.D.; Hospital Israelita Albert Einstein; Hospital do Coracao; Brazilian Research In Intensive Care Network; Ache Laboratorios Farmaceuticos S.A. Not yet recruiting
Conditions: Pouchitis; Crhon's Disease Like of the Pouch Intervention: Other: CDED diet Sponsor: Tel-Aviv Sourasky Medical Center Not yet recruiting
Analytical ChemistryDOI: 10.1021/acs.analchem.9b05278
ConclusionsThis study provides estimates of morbidity associated with the rectal stump after subtotal colectomy for IBD. A closed intra-abdominal stump seems to be associated with the highest rate of pelvic abscess/sepsis. Further work in form of an international collaborative project would allow individual patient data analysis and identification of risk factors for complications.