Squamous cell carcinoma of the bladder presented with spontaneous intraperitoneal bladder rupture: A case report

Conclusionhigh index of clinical suspicion and the timely diagnosis can lead to a more favorable outcome.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research

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BACKGROUND: Emissions from vehicles are composed of heterogeneous mixtures of hazardous substances; several pollutants such as Polycyclic Aromatic Hydrocarbons (PAHs) are amongst the most dangerous substances detected in urban monitoring. A cohort of traff...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Occupational Issues Source Type: news
Contributors : Zhang Gao ; Tian TianSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensImmune checkpoint blockade (ICB) therapy provides remarkable clinical gains, where melanoma is at the forefront of its success. However, only a subset of patients with advanced tumors currently benefit from these therapies, which at times incur considerable side-effects and costs. Constructing such predictors of patient ’s response has remained a serious challenge due to the complexity of the immune response and the shortage of large ICB-treated patient cohorts including both omics and response d...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Contributors : Yanjiao Li ; KunShan Zhang ; Jiaoni Cheng ; Yaolong Wang ; Jie Liu ; Orion S Fan ; Xingfei Wu ; Pengfei Bao ; Qiong Bai ; Congtao Yu ; Hailiang Liu ; Zhaoxia Ma ; Xinpei Gao ; Lirong Li ; Jinxue Liu ; Change Liu ; Daiping Ma ; Bin Jiang ; Fangyun Chen ; Shu Liang ; Qi Gu ; Zhuowei Yu ; Zhaojie Wang ; Kunhua Wang ; Yi E Sun ; Min HuSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensMesenchymal stem cells (MSCs) exist in many tissues and have emerged as promising candidates for therapeutic interventions. While MSCs may be used to reverse aging, they themselves also age. For ...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Authors: Kyritsi F, Loffredo CA, Zheng YL, Philips G, Amr S Abstract We investigated gender differences in the histopathologic presentation of bladder cancer cases in Egypt, where both urothelial cell carcinoma (UC) and squamous cell carcinoma (SCC) types are highly prevalent. We used logistic regression to estimate the unadjusted (OR) and adjusted odds ratio (AOR) and 95% confidence interval (CI) of the associations between gender and different histopathologic and sociodemographic parameters of 2,186 confirmed cases of primary bladder cancer (1,775 males and 411 females; 784 SCC and 1,402 UC). There were no statis...
Source: Advances in Urology - Category: Urology & Nephrology Tags: Adv Urol Source Type: research
This study aimed to investigate the expression of cyclin D1 and hnRNP-K in relation to the pathological findings in bladder cancer including the type, grade, muscle invasion and bilharzial association. Methods: We studied the immunoexpression; as regard the percentage, intensity and score of both cyclin D1 and hnRNP-K in different bladder lesions including 10 cases of cystitis; 10 cases of carcinoma insitu (CIS), 20 cases of Squamous cell carcinoma (SCC) and 66 cases of urothelial carcinoma (UC). Results: High expression of cyclin D1 was found in UC compared to other groups (p
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
AbstractA case of cystitis occurring after administration of nivolumab, an anti-programmed death-1 antibody, which was considered to be an immune-related adverse event, is reported. A 62-year-old man with pulmonary squamous cell carcinoma (T4N0M1a Stage IV) was being treated with nivolumab as fourth-line chemotherapy. He was hospitalized for a fever and diarrhea after 3 courses. Fasting and antibiotic medication reduced the fever and alleviated the diarrhea. He then developed cystitis with no evidence of infection. Cystoscopy showed diffused redness and erosion of the bladder mucosa; urine cytology was negative. Imaging ex...
Source: International Cancer Conference Journal - Category: Cancer & Oncology Source Type: research
Conclusion:EGFR and TGF α could be used as prognostic predictors in early stage and grade of bladder cancer cases, especially those with schistosomal association. In addition they can help in selecting patients who can get benefit from anti-EGFR molecular targeted therapy.Curr Urol 2015;9:192-201
Source: Current Urology - Category: Urology & Nephrology Source Type: research
Uterine cervical carcinoma secondarily involving the genitourinary tract is rarely documented histologically. These tumors present a unique diagnostic challenge as they can appear morphologically similar to urothelial carcinoma as well as primary squamous cell carcinoma and primary adenocarcinoma of the bladder. Genitourinary consult cases at the Johns Hopkins Hospital from 1984 to the present were searched for cases in which the differential diagnosis was primary bladder carcinoma versus secondary involvement by cervical carcinoma. We identified 10 cases that met these criteria and evaluated them by immunohistochemistry f...
Source: The American Journal of Surgical Pathology - Category: Pathology Tags: Original Articles Source Type: research
The objective of this study was to compare the effect of combined external beam radiotherapy (EBRT) and Californium (Cf)-252 neutron intracavity brachytherapy (ICBT) on cervical squamous versus adenocarcinoma. A total of 106 patients with stage IB–IIIB cervical cancer were accrued between January 2005 and May 2011 and divided into squamous cell carcinoma (SCC) and adenocarcinoma (AC) as a pair with 53 patients in each group according to tumor size, stage, age, and hemoglobin level using matched-pair design. The whole pelvic EBRT was performed with 2 Gy/fraction, 4 fractions/week. The total dose was 48–54&n...
Source: Medical Oncology - Category: Cancer & Oncology Source Type: research
Conclusion High-stage and -grade bladder malignancies expressed HER2 much more than did benign lesions. FISH is more sensitive for detecting HER2 expression. The treatment of HER2-positive tumours might benefit from novel targeted-treatment protocols.
Source: Arab Journal of Urology - Category: Urology & Nephrology Source Type: research
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