Continuous positive airway pressure for obstructive sleep apnoea does not improve asthma control

Respirology, EarlyView.
Source: Respirology - Category: Respiratory Medicine Authors: Source Type: research

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Obstructive sleep apnoea (OSA) syndrome, the most frequent sleep ‐disordered breathing, is a comorbidity of asthma, whose prevalence covers about 49.5% of asthmatic adult patients. A 61‐year‐old female patient, affected by severe allergic asthma and obesity, started treatment with omalizumab and underwent polysomnography showing a severe OSA pattern (apnoea /hypopnoea index (AHI): 72.7). After six months, she showed functional improvement and good asthma symptoms control and underwent a new polygraphy for the persistence of the night symptoms which showed an ameliorated, despite still severe, OSA pattern (AHI: 31.9)....
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: Case Report Source Type: research
PMID: 32027809 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - Category: Respiratory Medicine Authors: Tags: Am J Respir Crit Care Med Source Type: research
PMID: 32027805 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - Category: Respiratory Medicine Authors: Tags: Am J Respir Crit Care Med Source Type: research
This study is aimed to estimate the prevalence of sleep impairments among asthmatic patients and examine the relationship between sleep quality, asthma control, rhinitis symptoms, and sociodemographic characteristics. METHODS: The present study adopted the observational cross-sectional research design that has been designed by the Italian Respiratory Society and used valid assessments to measure the study variables. RESULTS: Data from 1150 asthmatic patients (mean age 51.01 years ± 16.03) were subjected to analysis. 58.3% of the patients had impaired sleep quality (Pittsburgh Sleep Quality Index [PSQI] total...
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
The occurrence and sequelae of disorders that lead to hypoxic spells such as asthma, chronic obstructive pulmonary disease, and obstructive sleep apnea (OSA) exhibit daily variance. This prompted us to examine the interaction between the hypoxic response and the circadian clock in vivo. We found that the global transcriptional response...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biological Sciences Source Type: research
CONCLUSIONS: Outpatient revision hip arthroplasty is safe in selected patients undergoing minor or partial revisions. Presence of medical comorbidities was not associated with risk of complications. Medical optimisation and a multimodal programme to mitigate risk of blood loss and reduce narcotic need facilitate the safe performance of arthroplasty in an outpatient setting. PMID: 31849244 [PubMed - as supplied by publisher]
Source: Hip International - Category: Orthopaedics Authors: Tags: Hip Int Source Type: research
Abstract Obstructive sleep apnea (OSA) and asthma are highly prevalent chronic respiratory disorders. Beyond frequent coexistence arising from their high prevalence and shared risk factors, these disorders feature a reciprocal interaction, whereby each disease impacts the severity of the other. Emerging evidence implicates airway and systemic inflammation, neuroimmune interactions, as well as effects of asthma-controlling medications (corticosteroids) as factors predisposing patients with asthma to OSA. Conversely, undiagnosed or inadequately treated OSA adversely affects asthma control, partly via effects of inte...
Source: American Journal of Respiratory and Critical Care Medicine - Category: Respiratory Medicine Authors: Tags: Am J Respir Crit Care Med Source Type: research
ConclusionsHospitalization for HRF is associated with a high morbidity and mortality. Our observation that home oxygen use was associated with increased mortality suggests that oxygen use could be a risk factor for death in patients with HRF.
Source: Lung - Category: Respiratory Medicine Source Type: research
We examined 3,917 children (age 4 ‐13 years) who were enrolled in a cross‐sectional study conducted in Seongnam, Korea. Their parents completed the Pediatric Sleep Questionnaire (PSQ) for evaluation of OSAS and the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire for evaluation of rhinitis. Clinical biomarkers, including total eosinophil count and neutrophil‐lymphocyte ratio (NLR), were measured in a subset of these children.ResultsOSAS and rhinitis had prevalences of 4.0% and 43.5%, respectively. Body mass index (P
Source: The Clinical Respiratory Journal - Category: Respiratory Medicine Authors: Tags: ORIGINAL ARTICLE Source Type: research
Purpose of review Severe asthma is often associated with numerous comorbidities that complicate disease management and affect patient's outcomes. They contribute to poor disease control and mimic asthma symptoms. Although some comorbidities such as obstructive sleep apnea, bronchiectasis, and chronic obstructive pulmonary disease are generally well recognized, many other may remain undiagnosed but may be detected in an expert specialist setting. The management of comorbidities seems to improve asthma outcomes, and optimizes therapy by avoiding overtreatment. The present review provides recent knowledge regarding the most...
Source: Current Opinion in Pulmonary Medicine - Category: Respiratory Medicine Tags: ASTHMA: Edited by Nicola A. Hanania, Zuzana Diamant, and Maarten van den Berge Source Type: research
More News: Asthma | Obstructive Sleep Apnea | Respiratory Medicine | Sleep Disorders | Sleep Medicine