Outcomes of Revision Joint Arthroplasty Due to Metal Allergy and Hypersensitivity: A Systematic Review.

Outcomes of Revision Joint Arthroplasty Due to Metal Allergy and Hypersensitivity: A Systematic Review. Surg Technol Int. 2018 Jul 05;33: Authors: Jauregui JJ, Desai SJ, Hodges V, Hariharan A, Newman JM, Adib F, Maheshwari AV Abstract BACKGROUND: Lower extremity total joint arthroplasty (TJA) is one of the most successful orthopaedic procedures. However, it is estimated that as many as 10% to 20% of TJAs could fail due to various well-known causes. Furthermore, metal allergy-related complications have recently gained attention as one of the potential causes of failure when the common reasons have been excluded. Reported symptoms from metal allergy can include chronic eczema, joint effusions, joint pain, and limited range of motion. Few studies have explored the outcomes of patients undergoing revisions due to allergic complications. The aim of our study is to quantitatively evaluate the outcomes of revision joint arthroplasty due to metal allergy and hypersensitivity. PMID: 29985516 [PubMed - as supplied by publisher]
Source: Surgical Technology International - Category: Surgery Tags: Surg Technol Int Source Type: research

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Of the 8,000 Californians who will contract Valley Fever this year, most will recover without treatment, and those with more serious cases will require an antifungal medication that clears the infection. But a few will experience a life-threatening form of the disease that ravages the body for reasons unknown.Now, an experimental treatment used by physicians atUCLA Mattel Children ’s Hospital that cured a 4-year-old boy may provide an explanation — and a method for manipulating the immune system to combat not just Valley Fever, but a host of infections.In February 2018, the Gonzalez-Martinez family traveled 200...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
In this study we used HPLC and LC/MS analysis, combined with a BATMAN-TCM platform, for detailed HPLC fingerprint analysis and network pharmacology of QP, and investigated the anti-inflammatory and antipruritic activities of QP on ACD induced by squaric acid dibutylester (SADBE) in mice. The BATMAN-TCM analysis provided information of effector molecules of the main ingredients of QP, and possible chronic dermatitis-associated molecules and cell signaling pathways by QP. In ACD mice, QP treatment suppressed the scratching behavior induced by SADBE in a dose-dependent manner and inhibited the production of Th1/2 cytokines in...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Discussion There are numerous microbial communities inhabited in the human body, which is critical to human health. The relationship between human microbiome and diseases received much attention from both medical and bioinformatics community recently. However, traditional methods to detect their association is costly and labor-intensive. Thus, we proposed here a new computational model called NBLPIHMDA to infer potential microbe-disease associations. NBLPIHMDA first combined known microbe-disease associations in HMDAD and the Gaussian interaction profile kernel similarity to construct disease similarity network and microb...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Abstract Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease isolated to the esophagus Food allergy is thought to play an important role in the pathophysiology of EOE. The aim of this study is to evaluate demographic features and sensitivity of patients with reference to common food allergens. Children with documented EoE were enlisted for this study. Skin prick test and patch test were done for all participants. Each test contained common food allergens. Other tests, such as evaluation of total IgE and eosinophil count, were also done. A total of 30 patients (the mean age of participants was 3&plu...
Source: Iranian Journal of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Iran J Allergy Asthma Immunol Source Type: research
Conclusions: Maternal exposure to indoor environmental NO2 causes allergic asthma-related consequences in offspring absent any subsequent lung provocation and potentiates the symptoms of allergic asthma in adult offspring following postnatal allergic sensitization and challenge; this response is associated with the Th2-based immune response and DNA methylation of the IL4 gene. https://doi.org/10.1289/EHP685 Received: 19 June 2016 Revised: 07 June 2017 Accepted: 19 June 2017 Published: 13 September 2017 Address correspondence to N. Sang, College of Environment and Resource, Shanxi University, Taiyuan, Shanxi 030006, P...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
We read with great interest the landmark article by Gaul1 in which 16 individuals with positive patch test results to nickel received additional patch testing to inorganic and organic substances and more than half developed multiple sensitivities after the primary nickel sensitization. Notably, the patients with multiple sensitivities had developed more extensive dermatoses, had higher recurrence rates (characterized by decreased pain sensation, uncontrollable pruritus, and chronic eczema), and required multiple hospitalizations.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Correspondence Source Type: research
This holiday season we are all in search of the perfect gift. What is the one thing you truly desire? Don’t you think we all want it? What if you were handed a beautifully wrapped box containing a miraculous tool that caused dramatic weight loss without limiting calories or requiring exercise? What if this gift reduced appetite, shrunk belly fat, dropped your dress size into the single digits, and accomplished all of this while sparing you from a Biggest Loser sob fest? What if that same gift freed you from acid reflux, heartburn, bowel urgency, and diarrhea, but also improved mood, increased energy, deepened sleep, ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Dr. Davis Priceless Gift Weight loss Wheat allergy Wheat Belly Wheat Belly Lifestyle Wheat Belly Total Health Wheat Watch Wheat-Free Lifestyle Detox diabetes gluten gluten-free grain grains Source Type: blogs
This holiday season we are all in search of the perfect gift. What is the one thing you truly desire for yourself and your family? Don’t you think we all want it? What if you were handed a beautifully wrapped box containing a miraculous tool that caused dramatic weight loss without limiting calories or requiring exercise? What if this gift reduced appetite, shrunk belly fat, dropped your dress size into the single digits, and accomplished all of this while sparing you from a Biggest Loser sob fest? What if that same gift freed you from acid reflux, heartburn, bowel urgency, and diarrhea, but also improved mood, incre...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Dr. Davis Priceless Gift Weight loss Wheat allergy Wheat Belly Wheat Belly Lifestyle Wheat Belly Total Health Wheat Watch Wheat-Free Lifestyle Detox diabetes gluten gluten-free grain grains Source Type: blogs
If you're one of the more than 20 million Americans who suffer from chronic kidney disease (CKD), your doctor has probably told you there isn't much they can do for you. Mainstream medicine doesn't have a cure for CKD. What they do have is a lot of drugs to treat the symptoms of it. And most of the drugs will leave you worse off than before you started taking them… Like ESAs, which are prescribed to treat anemia caused by chronic kidney disease. These dangerous drugs can cause strokes, heart attacks, blood clots and seizures. And if your kidneys fail, your only options are dialysis or a kidney transplant...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging Source Type: news
By Cynthia Sass, MPH, RD Suspect you might have a sensitivity to gluten or dairy, but aren't sure which is the culprit? You might be considering trying an elimination diet. This short-term eating plan has gained popularity recently as a way to identify potential food issues, including allergies, intolerances, and triggers of irksome symptoms--from bloating, joint pain, and fatigue to skin issues like eczema. While there's no one-size-fits-all protocol, an elimination diet typically involves two phases. In the first, several foods are eliminated for at least four weeks, sometimes eight. Then, those foods are added back, o...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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