New chalcone derivative exhibits antiproliferative potential by inducing G2/M cell cycle arrest, mitochondrial-mediated apoptosis and modulation of MAPK signalling pathway.

In conclusion, our data showed ability of 1C to suppress cancel cell growth and provide the rationale for further in vivo study.
PMID: 29981726 [PubMed - as supplied by publisher]

Source: Chemico-Biological Interactions - July 5, 2018 Category: Molecular Biology Authors: Takac P, Kello M, Pilatova MB, Kudlickova Z, Vilkova M, Slepcikova P, Petik P, Mojzis J Tags: Chem Biol Interact Source Type: research