Prenylated isoflavones from the stem bark of Erythrina sacleuxii

Publication date: August 2018Source: Phytochemistry Letters, Volume 26Author(s): Japheth O. Ombito, Runner R.T. Majinda, Ishmael B. Masesane, Gomotsang Bojase, Anja Schüffler, Till OpatzAbstractTwo new prenylated isoflavones, named erysacleuxin A (1) and B (2), along with eight known compounds, biochanin A (3), 5′-(3-methylbut-2-enyl)pratensein (4), 7-demethylrobustigenin (5), 3′-(3-methylbut-2-enyl)biochanin A (6) abyssinone V-4′-methyl ether (7), sigmoidin E (8), erythrinasinate (9), and burtinone (10) were isolated from the stem bark of Erythrina sacleuxii Hua (Leguminosae). The structures were determined based on spectroscopic and spectrometric data. All isolated compounds were evaluated for antifungal activity against Botrytis cinerea, Candida albicans, Eremothecium coryli, Penicillium notatum, Pyricularia oryzae, and Rhizomucor miehei with compounds 3, 4 and 6 showing weak to moderate activity against P. oryzae and R. miehei.Graphical abstract

Source: Phytochemistry Letters - July 11, 2018 Category: Chemistry Source Type: research