Toxic effect of Moringa peregrina seeds on histological and biochemical analyses of adult male Albino rats

In this study, Moringa peregrina seeds, grown in high elevation mountain in Saint Catherin area, were investigated and evaluated for their toxicity with respect to its topological potential through histological and biochemical studies in Albino rats. Daily doses of 0, 500, 1000 and 2000 mg/kg body weight of dry seed of M. peregrina were administered orally to 4 groups of rats for 14 days. Biochemical and histopathological results were evaluated by standard methods. Measured biochemical parameters, insulin, albumin, total protein, creatinine, urea, uric acid, Follicle-stimulating hormone, Luteinizing hormone and Testosterone, revealed normal levels compared to control group. However, measured level of blood sugars, cholesterol, triglyceride and liver enzyme, displayed significant decreases. No histopathological changes were detected in the body tested organs. In consequences, intake of different doses of M. peregrina, even high one, exhibit no organ toxicity and are safe for human use.Graphical abstract
Source: Toxicology Reports - Category: Toxicology Source Type: research

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Source: Life Sciences - Category: Biology Source Type: research
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Source: Australian Health Information Technology - Category: Information Technology Authors: Source Type: blogs
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Source: Journal of Zhejiang University. Science. B. - Category: Universities & Medical Training Source Type: research
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Source: Journal of Cardiovascular Nursing - Category: Nursing Tags: ARTICLES: Women and Cardiovascular Disease Source Type: research
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Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
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Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
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