New research highlights: Impact of chronic ingestion of white kidney beans (Phaseolus vulgaris L. var. Beldia) on small-intestinal disaccharidase activity in Wistar rats

The objective of this study was to assess the gavage effects of a raw Beldia bean variety on the brush border disaccharidase activities in the jejunal mucosa of Wistar rats. Twenty young adult male rats were randomly assigned into 2 groups of 10 rats each: Control, rats were gavaged with 300 mg of a rodent pellet flour suspension (RPFS); Experimental, rats were orogastrically fed a dose of 300 mg Beldia bean flour suspension (BBFS). Prior to determining the disaccharidase activity by Dahlqvist method, the blood and stool specimens were collected on day 10. The sera and feces were screened for the presence of lectins by serologic and hemagglutination assays. The results showed that the brush border maltase and sucrase activities were significantly diminished but lactase activity did not undergo any change in BBFS-gavaged animals as compared with control. Preliminary immunobiochemical assays revealed the absence of lectins in the systemic circulation and feces of rats, but further work is required to prove this. Overall, the dietary administration of BBFS caused depression of the activity of the small intestinal enzymes maltase and sucrase.Graphical abstract
Source: Toxicology Reports - Category: Toxicology Source Type: research

Related Links:

ConclusionIn our study, the Met-allele was associated with higher stress levels. To the best of our knowledge, this is the first study investigating this area. The findings from this study should trigger more investigators to focus on the impact of stress, due to the potential effects of these genes, on medical students.
Source: Journal of Taibah University Medical Sciences - Category: Universities & Medical Training Source Type: research
ConclusionsAlpha-synchronized rTMS of left DLPFC is feasible, safe and has specific single-session neuromodulatory effects in patients with antidepressant-resistant MDD. Future studies need to further elucidate the mechanisms, optimize the parameters and investigate the therapeutic potential and efficacy of brain oscillation-synchronized rTMS in MDD.
Source: Brain Stimulation - Category: Neurology Source Type: research
João A. P. Coutinho It was recently shown that tetramethylammonium chloride presented negative deviations to ideality when mixed with tetraethylammonium chloride or tetrapropylammonium chloride, leading to a strong decrease of the melting points of these salt mixtures, in a behavior akin to that observed in the formation of deep eutectic solvents. To better rationalize this unexpected melting point depression between two structurally similar compounds devoid of dominant hydrogen bonding capability, new solid–liquid equilibria data for tetramethylammonium-based systems were measured and analyzed in this...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Publication date: Available online 10 October 2019Source: NeuroImageAuthor(s): Spurny B, Seiger R, Moser P, Vanicek T, M.B. Reed, Heckova E, Michenthaler P, Basaran A, Gryglewski G, Klöbl M, Trattnig S, Kasper S, Bogner W, Lanzenberger RAbstractNeural plasticity is a complex process dependent on neurochemical underpinnings. Next to the glutamatergic system which contributes to memory formation via long-term potentiation (LTP) and long-term depression (LTD), the main inhibitory neurotransmitter, GABA is crucially involved in neuroplastic processes. Hence, we investigated changes in glutamate and GABA levels in the brai...
Source: NeuroImage - Category: Neuroscience Source Type: research
Conclusions: TR2 had a positive effect on the office workers' energy expenditure, blood parameters, depression, fatigue, and productivity. PMID: 31603033 [PubMed - as supplied by publisher]
Source: International Journal of Occupational Safety and Ergonomics - Category: Occupational Health Tags: Int J Occup Saf Ergon Source Type: research
Conclusion: Previous suicide attempt, smoking, unemployment, and suffering from at least one mental disorder were the significant predictors of suicide death. Among mental disorders, major depressive disorder and substance use disorder were the most prevalent mental health problems. PMID: 31602433 [PubMed]
Source: Accident and Emergency Nursing - Category: Emergency Medicine Authors: Tags: Arch Acad Emerg Med Source Type: research
Publication date: Available online 12 October 2019Source: Physiology &BehaviorAuthor(s): Qingfeng Xiao, Ze Xiong, Chunan Yu, Jiafeng Zhou, Qichen Shen, Liangliang Wang, Xiaoxian Xie, Zhengwei FuAbstractDepression is the leading cause of mental health-related disease globally, and it affects an estimated 300 million people worldwide. However, its physiological causes are not fully understood. Since available antidepressants fail to achieve complete disease remission, treating diversification of depression may be a useful contribution. Crocin, one of the main glycosylated carotenoids of saffron, has been found to have nu...
Source: Physiology and Behavior - Category: Physiology Source Type: research
Neurological insights into how the brain processes stress, and how it can develop into depression, have led to new interventionsIt ’s a damp, midweek afternoon. Even so, Cardiff’s walk-in stress management course has pulled in more than 50 people. There are teenagers, white-haired older people with walking aids, people from Caucasian, Asian and Middle Eastern backgrounds. There is at least one pair who look like a parent an d child – I’m unsure who is there to support whom.The course instructor makes it clear that she is not going to ask people to speak out about their own stress levels in this firs...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Neuroscience Depression Anxiety Mental health Society Psychology Cities Source Type: news
CONCLUSION: LZT treatment appears to be a feasible, non-pharmacological therapy amenable to SMs. Results from this pilot study promote further investigation of LZT as an intervention for SMs with persistent symptoms following TBI. PMID: 31603218 [PubMed - as supplied by publisher]
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
Authors: Caetano R, Vaeth PAC, Canino G Abstract OBJECTIVE: The purpose of this study was to update estimates of comorbidity between lifetime alcohol use disorder (AUD) severity and lifetime major depressive disorder (MDD) in San Juan, Puerto Rico. METHOD: Data are from a household random sample of 1,510 individuals (816 female) 18-64 years of age in San Juan, Puerto Rico. AUD and MDD identification follow criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition and Fourth Edition, respectively, both implemented with the Composite International Diagnostic Interview (CIDI). It is po...
Source: Journal of Studies on Alcohol and Drugs - Category: Addiction Tags: J Stud Alcohol Drugs Source Type: research
More News: Depression | Diets | Green Beans | Nutrition | Study | Toxicology | Urology & Nephrology