Hiperglucemia inducida por estrés en pacientes ancianos hospitalizados no críticos

ConclusionesLa HE en pacientes ancianos se asoció a las complicaciones hospitalarias, pero no a la mortalidad por todas las causas, comparado con pacientes con diabetes o con pacientes normoglucémicos.AbstractAimsHospital complications and hyperglycemia are common in elderly patients during hospitalization. Our aim was to analyze the relationship between hyperglycemia and hospital complications in an ageing population.MethodsWe conducted an observational study to evaluate the association between maximum blood glucose (MBG) levels and hospital complications. Patients were stratified according to the quartiles of MBG levels. Diabetes mellitus (DM) was determined by patient history and/or admission glycated hemoglobin (HbA1c) level ≥ 6.5%. Hyperglycemia in patients without DM was defined as stress-induced hyperglycemia (SH). The composite primary end-point included frequent complications and/or all-cause hospital mortality.ResultsAmong 461 patients, mean age 80 ± 7.5 years, 238 (51.6%) patients had DM, 20 had undiagnosed DM, and 162 (35.1%) developed hospital complications. Patients with complications had higher mean daily BG levels (215 ± 84 vs 195 ± 85 mg/dl, P < .01). The incidence of complications was directly associated with severity of hyperglycemia according to the quartiles of MBG levels in patients without DM, namely SH (< 140 mg/dl, 22.2%; 140-185 mg/dl, 40%; 186-250 mg/dl, 47%;> ...
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research