Fever and systemic inflammatory response syndrome after retrograde intrarenal surgery: Risk factors and predictive model
In conclusion, high stone burden, long surgical time, positive stone culture, high pre-operative CRP and the presence of diabetes mellitus was could increase the risk of fever or SIRS after RIRS for kidney stone. The constructed nomograms could help clinicians in evaluating the risk for post-operative infectious complications.
Publication date: 12 April 2020Source: Nutrition, Metabolism and Cardiovascular Diseases, Volume 30, Issue 4Author(s): Huanhuan Wang, Ying Song, Xiaofang Tang, Jingjing Xu, Ping Jiang, Lin Jiang, Zhan Gao, Jue Chen, Lei Song, Yin Zhang, Xueyan Zhao, Shubin Qiao, Yuejin Yang, Runlin Gao, Bo Xu, Jinqing Yuan, Lijian Gao
CONCLUSION: Rates of perinatal complications in our series are more reassuring than the ubiquitously quoted rates from small and dated studies. The diagnosis of primary hyperparathyroidism may be easily missed during pregnancy, owing to its non-specific presentation. A high index of suspicion and measurement of ionized calcium levels is encouraged, especially for patients with excessive nausea and vomiting, nephrolithiasis, atypical presentations of hypertensive disorders, or isolated polyhydramnios. Mild degrees of calcium derangement do not preclude adverse perinatal outcomes. Surgery appears to be safe, even in the thir...
Publication date: Available online 2 April 2020Source: Journal of the Formosan Medical AssociationAuthor(s): Chun-Wei Lee, Shu-Hao Wu, Wen-Chi Chiu, Shih-Tzer Tsai, Tzuo-Yun Lan
Authors: Alcázar-Leyva S, Zapata E, Bernal-Alcántara D, Gorocica P, Alvarado-Vásquez N Abstract Although thiamine pyrophosphate (TPP) is considered a protective agent for endothelial cells, it is still unknown if this is associated with nitric oxide (NO) synthesis. Our aim was to evaluate the synthesis of NO in endothelial cells incubated with TPP and high glucose concentrations. Endothelial cells from the umbilical cord vein from newborns (n = 20), were incubated with 5, 15 or 30 mmol/L glucose, in absence or presence of 0.625 mg/ml of TPP. Our results showed a significant...
In this study, we aimed to analyze the expression of glycan-processing genes in DRG neurons from a leptin-deficient genetic mouse model of diabetes (db/db). Transcriptomic analysis revealed that several glycan-processing genes encoding for glycosyltransferases and sialic acid-modifying enzymes were upregulated in diabetic conditions. Functional analysis of these enzymes on recombinant Cav3.2 revealed an unexpected loss-of-function of the channel. Collectively, our data indicate that diabetes is associated with an alteration of the glycosylation machinery in DRG neurons. However, individual action of these enzymes when test...
DIABETES type 2 symptoms include feeling very tired, unexplained weight loss, and passing more urine than normal. But you could also be at risk of high blood sugar signs if you pass more urine than normal - how many toilet trips a day is normal?
Publication date: Available online 2 April 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Samit Ghosal, Sumit Sengupta, Milan Majumder, Binayak Sinha
DiabetesMine gets hands on, testing out powdered glucose packets for treating low blood sugar with diabetes.
Publication date: Available online 2 April 2020Source: Pharmacological ResearchAuthor(s): Ke Su, Bo Yi, Bi-qing Yao, Tian Xia, Yi-fei Yang, Zhi-hao Zhang, Cheng Chen