Gastrointestinal Metastasis From Primary Lung Cancer. Case Series and Systematic Literature Review

Publication date: April 2018Source: Cirugía Española (English Edition), Volume 96, Issue 4Author(s): Andrea Balla, José D. Subiela, Jesús Bollo, Carmen Martínez, Carlos Rodriguez Luppi, Pilar Hernández, Yuliana Pascual-González, Silvia Quaresima, Eduard M. TargaronaAbstractAim of the present study is to report clinical characteristics and outcomes of patients treated in authors’ hospital for GI metastasis from primary lung cancer, and to report and analyze the same data concerning patients retrieved from a systematic literature review.We performed a retrospective analysis of prospectively collected data, and a systematic review using the Meta-analysis Of Observational Studies in Epidemiology (MOOSE) guidelines.Ninety-one patients were included, 5 patients from the authors’ hospital and 86 through PubMed database using the keywords “intestinal metastasis” AND “lung cancer”. The median time between primary lung cancer diagnosis and GI metastasis diagnosis was 2 months and the median overall survival was 4 months.This group of patients present a poor prognosis and the gold standard treatment is not defined. None of the reported treatments had a significant impact on survival.ResumenEl objetivo del presente estudio es describir las características clínicas y el manejo de los pacientes tratados en nuestra institución por metástasis GI de cáncer pulmonar primario;...
Source: Cirugia Espanola - Category: Surgery Source Type: research

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In this study, we discovered that miR-561 expression was downregulated in human NSCLC tissues and cell lines. The overexpression of miR-561 inhibited NSCLC cell proliferation and cell cycle G1-S transition and induced apoptosis. The inhibition of miR-561 facilitated cell proliferation and G1-S transition and suppressed apoptosis. MiR-561 expression was inversely correlated with P-REX2a expression in NSCLC tissues. P-REX2a was confirmed to be a direct target of miR-561 by using a luciferase reporter assay. The overexpression of miR-561 decreased P-REX2a expression, and the suppression of miR-561 increased P-REX2a expression...
Source: Oncology Research - Category: Cancer & Oncology Tags: Oncol Res Source Type: research
AbstractLung cancer is a leading cause of cancer death in Latinos. In a telephone survey, we assessed perceptions about lung cancer and awareness of, interest in, and barriers to lung screening among older current and former smokers. We compared Latino and non-Latino responses adjusting for age, sex, education, and smoking status using logistic regression models. Of the 460 patients who completed the survey (51.5% response rate), 58.0% were women, 49.3% former smokers, 15.7% Latino, with mean age 63.6  years. More Latinos believed that lung cancer could be prevented compared to non-Latinos (74.6% vs. 48.2%, OR 3.07, C...
Source: Journal of Immigrant and Minority Health - Category: International Medicine & Public Health Source Type: research
Authors: Gulak MA, Bornais C, Shin S, Murphy L, Smylie J, Pantarotto JR, Fung-Kee-Fung M, Maziak DE Abstract Background: Patients with lung cancer often experience stressful delays throughout the diagnostic phase of care. To address that situation, our multidisciplinary team created a "Navigation Day," during which patients partake in a single-day visit that comprises nurse-led teaching, social work, smoking cessation counselling, symptom control, and dedicated test slots for integrated positron-emission tomography and computed tomography (pet/ct), pulmonary function tests (pfts), and magnetic resonance i...
Source: Current Oncology - Category: Cancer & Oncology Tags: Curr Oncol Source Type: research
Condition:   Non-small Cell Lung Cancer Intervention:   Other: green tea Sponsors:   Xinqiao Hospital of Chongqing;   Daping Hospital and the Research Institute of Surgery of the Third Military Medical University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Cachexia; Cancer Intervention:   Other: multimodal Sponsor:   Aalborg University Hospital Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Metastatic Lung Cancer Intervention:   Behavioral: Pathways Sponsors:   Laurie McLouth;   National Cancer Institute (NCI) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Over the last decade, the rate of new lung cancer cases diagnosed in the United States has dropped 19% and the five-year survival rate has climbed 26%, according to a new report. Yet lung cancer still remains the leading cause of cancer death nationwide.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
LUNG cancer is one of the most common and serious types of cancer, with around 47,000 people diagnosed with the deadly condition every year in the UK. While there are usually no signs or symptoms in the early stages, as the disease progresses, people may notice a number of signs in their cough.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Researchers from Colorado have proposed expanding the diagnostic criteria for...Read more on AuntMinnie.comRelated Reading: U.K. group uses math to characterize lung disease on CT Genetic variation in lung airways elevates risk of COPD COPD severity mirrors lung cancer incidence AJR: Ultralow-dose CT can evaluate COPD Emphysema-related COPD on CT signals higher malignancy risk
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Authors: Ahmad TR, Doan T, Gonzales JA, Acharya NR, Tsui E PMID: 31710511 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
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