Freezing of gait in Parkinson's disease: functional neuroimaging studies of the frontal lobe.

CONCLUSIONS: Our study revealed greater hypometabolism in FDG PET studies, predominantly in right-sided-specific motor regions of the frontal lobe in FOG patients and greater frontal disfunction in neuropsychological tests in PD patients with FOG. These data suggest that FOG may be related to functional impairment of the circuits connecting the frontal lobe and the basal ganglia. PMID: 29985119 [PubMed - as supplied by publisher]
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research