Optimal HbA1c Cut-Off Point for Diagnosis of Type 2 Diabetes in Iranian Adults

Publication date: Available online 12 March 2018Source: Canadian Journal of DiabetesAuthor(s): Farideh Razi, Patricia Khashayar, Robabeh Ghodssi-Ghassemabadi, Mohsen Mehrabzadeh, Maryam Peymani, Fatemeh Bandarian, Ensieh Nasli EsfahaniAbstractObjectiveThe aim of this study was to evaluate the capability of HbA1c as a tool for identifying diabetic and prediabetic Iranian adults.MethodIn a cross-sectional population-based study, 1813 adults comprised of men and women aged 35-75 years without history of diabetes and hemoglobinopathies were included. Fasting blood glucose and HbA1c levels were obtained. According to ADA criteria, participants were categorized into three groups: newly diagnosed diabetes, prediabetic and healthy subjects. The optimal cut-off point for HbA1c in diabetes and prediabetes diagnosis was determined by studying the sensitivity and specificity of different cut-off points for HbA1c, while using different levels of fasting blood glucose as the gold standard.ResultsParticipants with newly diagnosed diabetes, were significantly older than prediabetic and healthy subjects (47.3±12.9, 44.6±13.0 and 39.2±14.1 yrs, respectively) and also had higher body mass index. As expected, the levels of fasting blood glucose (8.79±2.24, 6.01±0.38, and 4.97±0.4 mmol/L) and HbA1c (6.55±1.4, 5.61±0.61, 5.28±0.59) were significantly different between the groups (p
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research

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Source: Indian Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
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Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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