Hormone therapy in transgender women may deteriorate cardiovascular health

Hormone treatment given to transgender patients transitioning from male to female may significantly increase their risk of stroke, a study inAnnals of Internal Medicine reports. Reuters
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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Authors: PMID: 31083885 [PubMed - in process]
Source: Pain Physician - Category: Anesthesiology Tags: Am Fam Physician Source Type: research
Because stroke incidence increases with age, the absolute risk of stroke associated with standard-dose hormone therapy will be less among women close to the time of menopause, the group of women more likely to consider hormone therapy for vasomotor symptoms. These risks, which are rare but not negligible, should be considered by mid-life women and their physicians when discussing hormone therapy initiation and maintenance for treatment of vasomotor symptoms.
Source: Maturitas - Category: Primary Care Authors: Tags: INV34 Source Type: research
30 years ago, it was believed that there is a clear cut protective effect of estrogen in women with coronary artery disease. This was based on studies that monitored the outcomes of postmenopausal hormone therapy (MHT) in women with various basal clinical scenarios, such as myocardial infarction, coronary angiography or coronary artery bypass. These studies were observational, and treatment usually comprised of conjugated equine estrogen alone or combined with medroxyprogesterone acetate. However, results of randomized, placebo-controlled trials (secondary prevention, but mainly primary prevention) pointed at neutrality or...
Source: Maturitas - Category: Primary Care Authors: Tags: INV25 Source Type: research
Conclusion: These findings indicate that TBI differentially affects the levels of sex-steroid hormones in men and women patients. Plasma levels of testosterone could be a good candidate blood marker to predict recovery from unconsciousness after sTBI for male patients. Introduction Traumatic brain injury (TBI) is a major cause of death and disability worldwide and is increasing in incidence (1). Patients with acute severe TBI (sTBI) often develop severe disorders of consciousness, i.e., coma, minimally conscious state or vegetative state. Although many patients may regain consciousness during the 1-month post-TBI p...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Vincenzo Tigano1, Giuseppe Lucio Cascini2, Cristina Sanchez-Castañeda3, Patrice Péran4 and Umberto Sabatini5* 1Department of Juridical, Historical, Economic and Social Sciences, University of Magna Graecia, Catanzaro, Italy 2Department of Experimental and Clinical Medicine, University of Magna Graecia, Catanzaro, Italy 3Department of Clinical Psychology and Psychobiology, University of Barcelona, Barcelona, Spain 4ToNIC, Toulouse NeuroImaging Center, Université de Toulouse, Inserm, UPS, Toulouse, France 5Department of Medical and Surgical Sciences, University of Magna Graecia, Catanzaro, Ita...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Conclusions: Understanding unique vulnerabilities of the transgender community for cerebrovascular events is essential to provide culturally appropriate counseling for harm reduction.
Source: The Neurologist - Category: Neurology Tags: Case Report/Case Series Source Type: research
Transgender hormone therapy is associated with an increased risk for MI, stroke, and venous thromboembolism, underscoring the importance of patient counseling and close monitoring in this population.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Cardiology News Source Type: news
Research, published inCirculation, suggests that hormone therapy increases the risk of stroke in transgender women.Healio
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
(American Heart Association) People receiving hormone therapy during gender transition had an elevated risk for cardiovascular events, such as strokes, blood clots and heart attacks.Findings underscore the importance of counseling and close monitoring of transgender patients receiving hormone therapy.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
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