Low levels of intra-tumoural T cells in breast cancer identify clinically frail patients with shorter disease-specific survival

ConclusionsThis is the first study to show that low relative levels of intra-tumoural T cells are associated with inferior patient fitness. In contrast to T cells, we observed that intra-tumoural granulocytic cells displayed an inverse relationship with patient performance. Further research is needed to determine whether boosting the level of intra-tumoural T cells in older non-fit patients can result in improved outcome.
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research