Biologists discover process that neutralizes tumors

(University of California - San Diego) Researchers discovered an unexpected twist in the tumor vs. T cell battle. Tumors employ a protein called PD-L1 to blind T cells from carrying out their functions. PD-L1 protects tumors through a 'molecular brake' known as PD-1. Researchers have found that some tumor cells display not only their PD-L1 weapon, but also the PD-1 'brake,' essentially a neutralizing function. The unexpected mechanism that could help determine whether a cancer patient will respond to immunotherapy.

https://www.eurekalert.org/pub_releases/2018-07/uoc--bdp070918.php

Source: EurekAlert! - Cancer - July 10, 2018 Category: Cancer & Oncology Source Type: news