Parkinson's disease monitoring from gait analysis via foot-worn sensors

Publication date: Available online 28 June 2018Source: Biocybernetics and Biomedical EngineeringAuthor(s): Tunç Aşuroğlu, Koray Açıcı, Cağatay Berke Erdaş, Münire Kılınç Toprak, Hamit Erdem, Hasan OğulAbstractBackgroundIn Parkinson’s disease (PD), neuronal loss in the substantia nigra ultimate in dopaminergic denervation of the stiratum is followed by disarraying of the movements’ preciseness, automatism, and agility. Hence, the seminal sign of PD is a change in motor performance of affected individuals. As PD is a neurodegenerative disease, progression of disability in mobility is an inevitable consequence. Indeed, the major cause of morbidity and mortality among patients with PD is the motor changes restricting their functional independence. Therefore, monitoring the manifestations of the disease is crucial to detect any worsening of symptoms timely, in order to maintain and improve the quality of life of these patients.AimThe changes in motion of patients with PD can be ascertained by the help of wearable sensors attached to the limbs of subjects. Then analysing the recorded data for variation of signals would make it possible to figure an individualized profile of the disease. Advancement of such tools would improve understanding of the disease evolution in the long term and simplify the detection of precipitous changes in gait on a daily basis in the short term. In both cases the apperception of such events would contribute to improve the clinical decisi...
Source: Biocybernetics and Biomedical Engineering - Category: Biomedical Engineering Source Type: research