Development of a Risk Prediction Model and Clinical Risk Score for Isolated Tricuspid Valve Surgery

Publication date: July 2018Source: The Annals of Thoracic Surgery, Volume 106, Issue 1Author(s): Damien J. LaPar, Donald S. Likosky, Min Zhang, Patty Theurer, C. Edwin Fonner, John A. Kern, Steven F. Bolling, Daniel H. Drake, Alan M. Speir, Jeffrey B. Rich, Irving L. Kron, Richard L. Prager, Gorav Ailawadi, Investigators for the Virginia Cardiac Surgery Quality Initiative and the Michigan Society of Thoracic and Cardiovascular SurgeonsBackgroundAlthough tricuspid valve operations remain associated with high mortality (approximately 8% to 10%), no robust prediction models exist to support clinical decision making. We developed a preoperative clinical risk model with an easily calculable clinical risk score (CRS) to predict mortality and major morbidity after isolated tricuspid valve surgery.MethodsThe Society of Thoracic Surgeons database records were evaluated for 2,050 isolated TV repair and replacement operations for any etiology performed at 50 hospitals (2002 to 2014) in a number of states. Parsimonious preoperative risk prediction models were developed using multiple-level mixed effects regression to estimate mortality and composite major morbidity risk. Model results were utilized to establish a novel CRS for patients undergoing tricuspid valve operations. Models were evaluated for discrimination and calibration.ResultsOperative mortality and composite major morbidity rates were 9% and 42%, respectively. Final regression models performed well (both p
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research

Related Links:

Publication date: Available online 31 March 2020Source: Neurophysiologie CliniqueAuthor(s): Karim Jamal, Stéphanie Leplaideur, Chloé Rousseau, Sébastien Cordillet, Annelise Moulinet Raillon, Simon Butet, Armel Cretual, Isabelle Bonan
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
Authors: Tomita H PMID: 32224558 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
Functional MR images (fMRI) have uncovered decreased connectivity from excessive...Read more on AuntMinnie.comRelated Reading: MRI data show smoking, alcohol age the brain Brain MRI may predict alcohol abuse in teens PET, fMRI shed light on alcohol's effects on brain MRI links lifestyle factors to stroke, dementia risk fMRI shows what makes an angry drunk
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Contributors : Ashley McDonough ; Richard V Lee ; Shahani Noor ; Chungeun Lee ; Thu Le ; Michael Iorga ; Jessica L Phillips ; Sean Murphy ; Thomas M öller ; Jonathan R WeinsteinSeries Type : Expression profiling by arrayOrganism : Mus musculusStroke is the fifth leading cause of death in the United States and is a leading cause of serious long-term disability worldwide. Innate immune responses are critical in stroke pathophysiology, and microglia are key cellular effectors in the CNS response to ischemia/reperfusion. Using a transcriptional analysis approach, we identified a robust interferon (IFN)-stimulated gene res...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research
Contributors : Bing Han ; Honghong YaoSeries Type : Expression profiling by array ; Non-coding RNA profiling by arrayOrganism : Mus musculusAstrocyte activation is involved in the context of stroke. Our study provides a potential new therapeutic strategy to astrocyte activation in the context of stroke.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Non-coding RNA profiling by array Mus musculus Source Type: research
Stryker Neurovascular, AXS Vecta 71 Aspiration Catheter, Ref. Catalog No. INC-11129-115, Use By 2021-11-29, Rx Only, Sterile/EO, Manufactured For: Stryker Neurovascular 47900 Bayside Parkway, Fremont, CA 94538, UDI: (01)07613327459210(17)211129(10)00000-00 Stryker Neurovascular, AXS Vecta 71 Aspiration Catheter, Ref. Catalog No. INC-11129-125, Use By 2021-11-29, Rx Only, Sterile/EO, Manufactured For: Stryker Neurovascular 47900 Bayside Parkway, Fremont, CA 94538, UDI: (01)07613327459227(17)211129(10)00000-00 Stryker Neurovascular, AXS Vecta 71 Aspiration Catheter, Ref. Catalog No. INC-11129-132, Use By 2021-11-29, Rx Only,...
Source: Medical Device Recalls - Category: Medical Devices Source Type: alerts
Stryker Neurovascular, AXS Vecta 74 Aspiration Catheter, Ref. Catalog No. INC-11597-115, Use By 2021-11-29, Rx Only, Sterile/EO, Manufactured For: Stryker Neurovascular 47900 Bayside Parkway, Fremont, CA 94538, UDI: (01)07613327459241(17)211129(10)00000-00 Stryker Neurovascular, AXS Vecta 74 Aspiration Catheter, Ref. Catalog No. INC-11597-125, Use By 2021-11-29, Rx Only, Sterile/EO, Manufactured For: Stryker Neurovascular 47900 Bayside Parkway, Fremont, CA 94538, UDI: (01)07613327459258(17)211129(10)00000-00 Stryker Neurovascular, AXS Vecta 74 Aspiration Catheter, Ref. Catalog No. INC-11597-132, Use By 2021-11-29, Rx Only,...
Source: Medical Device Recalls - Category: Medical Devices Source Type: alerts
Heart failure, ischemic heart disease, stroke may contribute to link between air pollution and dementia
Source: The Doctors Lounge - Psychiatry - Category: Psychiatry Tags: Cardiology, Family Medicine, Geriatrics, Internal Medicine, Neurology, Psychiatry, Pulmonology, Journal, Source Type: news
Source: Risk Management and Healthcare Policy - Category: Health Management Tags: Risk Management and Healthcare Policy Source Type: research
Stroke is considered one of the major hurdles in applying Left Ventricular Assist Device (LVAD) technology to a broader population, and remains a leading cause of mortality and morbidity despite advances in both technology and management. In the general population, incidence of stroke in African Americans (AA) has been reported to be twice that of their Caucasian counterparts, and the mortality following stroke higher in AA. We sought to assess the effect of race on both rate of stroke, as well as post stroke survival in the LVAD population.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (212) Source Type: research
More News: Cardiology | Cardiovascular | Cardiovascular & Thoracic Surgery | Databases & Libraries | Dialysis | Emergency Medicine | Gastroschisis Repair | Heart | Heart Valve Surgery | Hemodialysis | Stroke